Prior history of traumatic brain injury among persons in the Traumatic Brain Injury Model Systems National Database.

Prior history of traumatic brain injury among persons in the Traumatic Brain Injury Model Systems National Database.
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DOI:
10.1016/j.apmr.2013.05.018
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发表时间:
2013-10
影响因子:
4.3
通讯作者:
Kolakowsky-Hayner S
Kolakowsky-Hayner S
中科院分区:
医学1区
文献类型:
--
作者:
Corrigan JD;Bogner J;Mellick D;Bushnik T;Dams-O'Connor K;Hammond FM;Hart T;Kolakowsky-Hayner S

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确定人口统计学、心理社会学和损伤相关特征与需要康复的中度或重度创伤性脑损伤(TBI)之前发生的创伤性脑损伤(TBI)之间的关联。二级数据分析。创伤性脑损伤模型系统住院康复设施。TBI后1、2、5、10、15或20年参与TBI模型系统国家数据库的患者(N = 4464)。不适用因TBI模型系统指数损伤前的TBI病史、指数损伤前的人口统计学和行为特征、指数损伤特征、指数损伤后的行为健康和总体结局。20%的队列在TBI模型系统指数损伤之前经历了TBI,其中80%是轻度的,40%发生在16岁之前。指数损伤前和损伤后的行为问题,特别是药物滥用,与先前的TBI高度相关。更严重的前指数损伤以及发生在6岁之前往往表现出更强的关联。出乎意料的是,指数TBI前的指数损伤程度较轻,入院和康复出院时功能更好。研究结果表明,早期生活TBI可能对随后的TBI后的康复有重要意义,特别是在恢复的慢性阶段预测行为健康问题。结果为早期TBI的潜在后果提供了额外的证据,即使是轻微的。
To determine the association between demographic, psychosocial, and injury-related characteristics and traumatic brain injury (TBI) occurring prior to a moderate or severe TBI requiring rehabilitation. Secondary data analysis. TBI Model System inpatient rehabilitation facilities. Persons (N = 4464) 1, 2, 5, 10, 15, or 20 years after TBI resulting in participation in the TBI Model System National Database. Not applicable. History of TBI prior to the TBI Model System Index injury, pre-Index injury demographic and behavioral characteristics, Index injury characteristics, post-Index injury behavioral health and global outcome. Twenty percent of the cohort experienced TBIs preceding the TBI Model System Index injuryd80% of these were mild and 40% occurred before age 16. Pre- and post-Index injury behavioral issues, especially substance abuse, were highly associated with having had a prior TBI. Greater severity of the pre-Index injury as well as occurrence before age 6 often showed stronger associations. Unexpectedly, pre-Index TBI was associated with less severe Index injuries and better functioning on admission and discharge from rehabilitation. Findings suggest that earlier life TBI may have important implications for rehabilitation after subsequent TBI, especially for anticipating behavioral health issues in the chronic stage of recovery. Results provide additional evidence for the potential consequences of early life TBI, even if mild.
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