Plasmacytoid dendritic cells infiltrating ovarian cancer are associated with poor prognosis.
Plasmacytoid dendritic cells infiltrating ovarian cancer are associated with poor prognosis.
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DOI:
10.4161/onci.18801
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发表时间:
2012-05-01
期刊:
影响因子:
7.2
通讯作者:
Bendriss-Vermare N
中科院分区:
文献类型:
--
作者:
Labidi-Galy SI;Treilleux I;Goddard-Leon S;Combes JD;Blay JY;Ray-Coquard I;Caux C;Bendriss-Vermare N
Using two different and complementary approaches (flow cytometry and immunohistochemistry) on two independent cohorts of ovarian cancer patients, we found that accumulation of plasmacytoid dendritic cells (pDC) in tumors is associated with early relapse. This deleterious effect of tumor-associated pDC was evident when they are present in cancer epithelium but not in lymphoid aggregates.
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影响因子:
11.2
作者:
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通讯作者:
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通讯作者:
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作者:
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通讯作者:
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