Synthesis of a cagelike hollow aluminosilicate with vermiculate micro-through-holes and its application to ship-in-bottle encapsulation of protein.
Synthesis of a cagelike hollow aluminosilicate with vermiculate micro-through-holes and its application to ship-in-bottle encapsulation of protein.
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DOI：
10.1002/smll.200800834
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发表时间：
2009
期刊：
影响因子：
13.3
通讯作者：
Toru Shiomi;T. Tsunoda;A. Kawai;S. Matsuura;F. Mizukami;K. Sakaguchi
中科院分区：
文献类型：
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作者：
Toru Shiomi;T. Tsunoda;A. Kawai;S. Matsuura;F. Mizukami;K. Sakaguchi
空心无机结构由于其潜在的应用前景而受到越来越多的关注，如无机催化剂载体、光学传感系统、存储胶囊和药物释放控制系统等空心结构的功能使用与其形态特性密切相关，即外观形状、内部空间和壳体结构特别是，连接中空结构内外空间的通孔的建筑设计对于输送所需的分子是必不可少的例如，通过孔径小于10nm的闭壳结构的扩散通常是一个缓慢的过程生物大分子，如蛋白质和DNA，不能通过存在于外壳上的传统介孔有效地渗透到中空颗粒的内部空间。为了增加渗透性和创造储存生物大分子的能力，需要在无机中空结构的外壳上建立微通孔。大多数用于开发中空无机纳米和微结构的制造方法都是基于直接模板方法，即使用牺牲的核心材料来创建内部空间，然后通过重复逐层沉积过程来构建外壳结构然而,所以
Hollow inorganic structures have received increasing attention because of their potential applications, such as inorganic catalyst carriers, optical sensing systems, storage capsules, and controlled-release systems for drug delivery.[1] The functional use of hollow structures is closely correlated with their morphological properties, that is, the exterior shape, the interior space, and the shell structure.[2] In particular, the architectural design of through-holes connecting the inner and outer spaces of hollow structures is indispensable for transporting desirable molecules.[3] For example, diffusion through closed-shell structures with pores< 10 nm in diameter is often a slow process.[4] Biomacromolecules, such as proteins and DNA, cannot effectively penetrate into the interior spaces of hollow particles through the conventional mesopores present on the shells. To increase the permeability and create the ability to store biomacromolecules, it is desirable to build micro-through-holes on the shells of inorganic hollow structures.Most fabrication methods employed in the development of hollow inorganic nano-and microstructures have been based on direct template methods that use sacrificial core materials to create interior space, and then the shell structure is built by repeating a layer-by-layer deposition process.[5] However, so