The Maturation Index of Colostrum and Milk (MICAM): A Measurement of Breast Milk Maturation
The Maturation Index of Colostrum and Milk (MICAM): A Measurement of Breast Milk Maturation
复制标题
初乳和乳汁的成熟指数 (MICAM)：母乳成熟度的测量
DOI：
10.1891/1061-3749.2.2.169
复制
发表时间：
1994
影响因子：
0.7
通讯作者：
P. Hill
中科院分区：
文献类型：
--
作者：
S. Humenick;D. Mederios;Theodora B. Wreschner;M. B. Walton;P. Hill
采用滤纸层析法建立了一种生物标记物--初乳和牛乳成熟指数（MIC AM）。MICAM由五种模式组成，用于测量母亲的母乳成熟率。本文记录了MICAM模式的生物学基础，即母乳乳状液的逐渐分解取决于甾醇和磷脂与牛奶中脂肪含量的比例。频率MICAM模式的一天，时间的牛奶收集，和评分员之间的可靠性解决和结构效度进行了探讨。这是Humenick在1987年报告的原始工具开发的部分复制。在这两项研究中，母乳喂养开始的时间，频率和母乳喂养事件的累积长度的变量显着相关的MICAM测量的早期牛奶成熟的预测因子。乳汁成熟率也是婴儿体重增加、持续母乳喂养周数和母婴母乳喂养满意度的预测因子。MICAM可用作临床筛查工具，以评估母乳喂养开始困难或延迟的情况下乳汁成熟的进展，并评估旨在支持哺乳的干预措施。
A biological marker, the Maturation Index of Colostrum and Milk (MIC AM), was developed using filter paper chromatography. The MICAM consists of five patterns used to measure the individual rate of breast milk maturation among mothers. This article documents the biological basis of MICAM patterns as a gradual breakdown of an emulsion of breast milk that is dependent on the ratio of sterols plus phospholipids to fat content of the milk. Frequencies of MICAM patterns by day, timing of the milk collection, and inter-rater reliability are addressed and the construct validity is explored. This was a partial replication of the original tool development reported by Humenick in 1987. In both studies, the variables of timing of breast-feeding initiation, frequency, and cumulative length of breast-feeding episodes were significantly correlated as predictors of early milk maturation as measured by the MICAM. Milk maturation rate was also significantly correlated as a predictor of infant weight gain, weeks of sustained breast-feeding, and maternal-infant breast-feeding satisfaction. The MICAM can be used as a clinical screening tool to assess the progress of milk maturation in cases where breast-feeding has had a difficult or delayed initiation, and to evaluate interventions designed to support lactation.