A naphthimide-based ratiometric fluorescent probe for selective and visual detection of phosgene in solution and the gas phase
A naphthimide-based ratiometric fluorescent probe for selective and visual detection of phosgene in solution and the gas phase
复制标题
基于萘酰亚胺的比率荧光探针，用于选择性和视觉检测溶液和气相中的光气
DOI：
10.1016/j.saa.2021.120789
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发表时间：
2022
期刊：
影响因子：
--
通讯作者：
Yin Jun
中科院分区：
文献类型：
--
作者：
Xu Zhiqiang;Luo Yabin;Hong Yu;Liu Ziru;Zhang Ming-Xing;Gu Shuang-Xi;Yin Jun
光气作为一种无色、剧毒、用途广泛的化学试剂，对公众健康和环境安全构成了潜在的严重威胁。因此，迫切需要开发一种简便、灵敏的光气检测方法。本文以4-取代1,8-萘酰亚胺单元为荧光基团，乙二胺为识别片段，研制了光气比例荧光探针（NED）。该探针与光气发生分子内环化反应，产生显著的比例荧光响应。与其他相关分析物相比，probened具有高灵敏度（LOD = 4.9 nM）、良好的比例荧光信号和对光气的高选择性。此外，还制备了能直观检测气态光气的试纸条。
As a colorless, highly toxic and widely used chemical reagent, phosgene poses a potentially serious threat to public health and environmental safety. Therefore, there is an urgent need to develop a simple and sensitive method for detecting phosgene. In this work, a ratiometric fluorescent probe (NED) for phosgene was developed by utilizing 4-substituted 1,8-naphthimide unit as the fluorophore and ethylenediamine as the recognition moiety. The probeNEDundergoes intramolecular cyclization reaction with phosgene, resulting in a remarkable ratiometric fluorescence response. The probeNEDdisplays high sensitivity (LOD = 4.9 nM), excellent ratiometric fluorescence signal, and high selectivity toward phosgene over other relevant analytes. In addition, paper test strip capable of visually detecting gaseous phosgene has also been fabricated.