Increase in the risk of type 2 diabetes during lockdown for the COVID19 pandemic in India: A cohort analysis
Increase in the risk of type 2 diabetes during lockdown for the COVID19 pandemic in India: A cohort analysis
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DOI：
10.1016/j.dsx.2020.06.020
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发表时间：
2020-09-01
影响因子：
10
通讯作者：
Misra, Anoop
中科院分区：
文献类型：
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作者：
Ghosal, Samit;Arora, Bhavya;Misra, Anoop
由于2019冠状病毒病（COVID 19）大流行导致的封锁可能导致体重增加并增加2型糖尿病（T2 DM）的风险。我们的目的是确定这种风险在显然nondiabetic individuals.Material方法：基线人口统计学和临床数据从100显然非糖尿病家庭成员（相关或无关）的2型糖尿病患者收集，直到49天的锁定和分析使用的XL-STAT统计软件。采用了双管齐下的分析战略。首先，分析了与年龄、性别、体重、家族史和运动模式相关的代谢风险概况。其次是使用一个既定的风险评估engine.Results的发展2型糖尿病的风险评估：有体重增加的趋势，在40%的队列中，16%的人口经历了2.1-5公斤的体重增加。当使用ADA风险引擎一起分析所有风险参数时，7%的人群中ADA糖尿病风险评分增加，高风险组中为6.66%。有3%的人口谁已经肥胖在baseline.Conclusion：体重增加的进一步增加，我们表明在49天的封锁在印度的T2 MD随之体重增加的风险增加。(C)2020年印度糖尿病。由爱思唯尔有限公司出版。保留所有权利。
Lockdown due to the Coronavirus disease 2019 (COVID 19) pandemic may cause weight gain and enhance the risk of type 2 diabetes mellitus (T2DM). We aimed to determine this risk in apparently nondiabetic individuals.Material methods: Baseline demographic and clinical data from 100 apparently non-diabetic household members (related or unrelated) of patients with type 2 diabetes mellitus were collected until 49 days of lockdown and analyzed using the XL-STAT statistical software. A two-pronged analytical strategy was employed. First, the metabolic risk profile related to age, sex, weight, family history, and exercise pattern was analyzed. This was followed by an assessment of the risk of developing type 2 diabetes using an established risk assessment engine.Results: There was a trend towards weight gain seen in 40% of the cohort, with 16% of the population experiencing a 2.1-5 kg weight increment. When all the risk parameters were analyzed together using the ADA risk engine, there was an increase in the ADA diabetes risk score in 7% of the population, with 6.66% in the high-risk group. There was a further increase in weight among 3% of the population who were already obese at baseline.Conclusion: We show an increased risk of T2MD consequent to weight gain during 49 days of lockdown in India. (C) 2020 Diabetes India. Published by Elsevier Ltd. All rights reserved.