A STANDARDIZED BREATH HOLDING TECHNIQUE FOR THE CLINICAL MEASUREMENT OF THE DIFFUSING CAPACITY OF THE LUNG FOR CARBON MONOXIDE
A STANDARDIZED BREATH HOLDING TECHNIQUE FOR THE CLINICAL MEASUREMENT OF THE DIFFUSING CAPACITY OF THE LUNG FOR CARBON MONOXIDE
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DOI：
10.1172/jci103402
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发表时间：
1957-01-01
影响因子：
15.9
通讯作者：
MORTON, JW
中科院分区：
文献类型：
--
作者：
OGILVIE, CM;FORSTER, RE;MORTON, JW
方法 之前 (1, 2) 已报道过的 DL 测量技术主要包括让受试者从其残余体积水平最大程度地吸入含有 10% 氦气 (He)、0.3% CO 和约 21% O2 的 N2 的气体混合物，保持一段测量时间，然后快速呼气。除第一升外，所有呼出气体均由操作员收集在袋子中，并作为肺泡气体进行分析。在任何 CO 被肺部吸收之前，该样品中存在的 CO 浓度是根据吸入的 He 的稀释度根据以下方程计算的：
METHODSThe technique for the measurement of DL, which has been reported be'fore (1, 2), consists essentially of having the subject make a maximal inspiration of a gas mixture containing 10 per cent helium (He), 0.3 per cent CO and approximately 21 per cent 02 in N2 from the level of his residual volume, hold it for a measured time, and then rapidly expire. All of this expiration except the first liter is collected in a bag by the operator and analyzed as alveolar gas. The CO concentration which was present in this sample before any CO had been absorbed in the lungs is calculated from the dilution of the inspired He according to the equation,