Levamisole-induced occlusive necrotising vasculitis in cocaine abusers: an unusual cause of skin necrosis and neutropenia.
Levamisole-induced occlusive necrotising vasculitis in cocaine abusers: an unusual cause of skin necrosis and neutropenia.
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DOI：
10.1111/j.1742-481x.2012.01027.x
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发表时间：
2013-10
影响因子：
3.1
通讯作者：
Kerr G
中科院分区：
文献类型：
--
作者：
Belfonte CD;Shanmugam VK;Kieffer N;Coker S;Boucree S;Kerr G
我们提出三个案例，描述了假定的左旋咪唑污染可卡因使用的各种皮肤表现。抗体介导的血管炎和中性粒细胞减少症在这些病例中是一致的发现，重复暴露导致不同的皮肤并发症。这种左旋咪唑引起的血管炎和中性粒细胞减少症的现象越来越多地被描述，并具有特征性的伤口表现，必须及早识别和治疗。
We present three cases describing the various skin manifestations of presumed levamisole-contaminated cocaine use. Antibody-mediated vasculitis and neutropenia were consistent findings in these cases and repeat exposure resulted in distinct dermatologic complications. This phenomenon of levamisole-induced vasculitis and neutropenia is being increasingly described and has characteristic wound manifestations that must be recognised and treated early.