Agrobacterium tumefaciens virulence locus pscA is related to the Rhizobium meliloti exoC locus.
Agrobacterium tumefaciens virulence locus pscA is related to the Rhizobium meliloti exoC locus.
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根癌农杆菌毒力位点 pscA 与苜蓿根瘤菌 exoC 位点相关。
DOI：
10.1128/jb.169.12.5835-5837.1987
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发表时间：
1987
影响因子：
3.2
通讯作者：
Thomashow,MF
中科院分区：
文献类型：
--
作者：
Marks,JR;Lynch,TJ;Karlinsey,JE;Thomashow,MF
根癌农杆菌和苜蓿根瘤菌都携带有相关的遗传位点，这些位点在致病力和共生关系中起重要作用。以前的研究表明，A. chvA和chvB与两个根瘤菌R.苜蓿根瘤菌共生位点ndvA和ndvB（T.迪伦湖耶尔皮S.斯坦菲尔德湖卡什亚普角道格拉斯，M. Yanofsky，E. Nester，D. R. Helinski和G. Ditta，Proc. Natl. Acad. Sci. USA 83：4403-4407，1986）。在这里，我们表明，这两种植物细菌具有额外的相关毒力/共生基因。遗传互补和DNA杂交实验结果表明，A. tumefaciens的exoC共生位点在结构和功能上与根瘤菌的exoC共生位点相关。苜蓿草。因此，A. tumefaciens和R.草木樨携带至少三个相关的遗传基因座，这些基因座在建立每种细菌与其各自宿主植物的相互作用中具有关键作用。
Agrobacterium tumefaciens and Rhizobium meliloti carry related genetic loci which have important roles in virulence and symbiosis. Previously, it was shown that two virulence loci of A. tumefaciens, chvA and chvB, are related to two R. meliloti symbiosis loci, ndvA and ndvB, respectively (T. Dylan, L. Ielpi, S. Stanfield, L. Kashyap, C. Douglas, M. Yanofsky, E. Nester, D. R. Helinski, and G. Ditta, Proc. Natl. Acad. Sci. USA 83:4403-4407, 1986). Here we show that these two phytobacteria possess additional related virulence/symbiosis genes. Results of genetic complementation and DNA hybridization experiments indicate that the pscA virulence locus of A. tumefaciens is structurally and functionally related to the exoC symbiosis locus of R. meliloti. Thus, A. tumefaciens and R. meliloti bear at least three related genetic loci that have crucial roles in establishing the interactions that each bacterium has with its respective host plants.