Effect of pH on the Efficacy of Sodium Hypochlorite Solution as Cleaning and Bactericidal Agents
Effect of pH on the Efficacy of Sodium Hypochlorite Solution as Cleaning and Bactericidal Agents
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pH值对次氯酸钠溶液清洁杀菌效果的影响
DOI：
10.4139/sfj.58.465
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发表时间：
2007
期刊：
影响因子：
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通讯作者：
Sadako Yamada
中科院分区：
文献类型：
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作者：
S. Fukuzaki;H. Urano;Sadako Yamada
本文研究了pH值对次氯酸钠（NaOCl）溶液清洗和杀菌荧光假单胞菌的效果。用pH值为5 ~ 12、含游离有效氯（AC）为120 ~ 1000 mg/L的NaOCl溶液清洗粘附有荧光假单胞菌细胞的氧化铝（Al_2 O_3）颗粒。从Al 2 O3表面去除荧光假单胞菌细胞的效率随着pH和AC浓度的增加而增加。有人发现，NaOCl溶液作为清洗剂的功效取决于解离的次氯酸根离子（-OCl）的浓度。而2.5mgAC/L的NaOCl溶液的杀菌活性随pH值从9.3降低到5.7而增加。活性荧光假单胞菌的对数相对减少量与AC浓度和时间的乘积成正比，灭活率取决于未解离的次氯酸（HOCl）的浓度。结果表明，NaOCl溶液的清洗和杀菌活性受溶液中HOCl和-OCl含量的影响。
The efficacy of sodium hypochlorite (NaOCl) solution as a cleaning and bactericidal agent against Pseudomonas fluorescens was studied as a function of pH. Alumina (Al2O3) particles on which P. fluorescens cells were irreversibly adhered were cleaned with NaOCl solutions of pH 5 to 12 containing free available chlorine (AC) of 120 to 1000mg/L. The efficiency of the removal of P. fluorescens cells from the Al2O3 surfaces increased with increasing pH and the AC concentration. It was found that the efficacy of NaOCl solution as a cleaning agent depended on the concentration of the dissociated hypochlorite ion (-OCl). On the other hand, the bactericidal activity of NaOCl solution of 2.5mg AC/L increased with decreasing pHs from 9.3 to 5.7. The logarithmic relative reductions of viable P. fluorescens were proportional to the product of the AC concentration and time, and the rate of inactivation depended on the concentration of undissociated hypochlorous acid (HOCl). Our results show that the cleaning and bactericidal activities of NaOCl solution are governed by the percentage of HOCl and -OCl existing in the solution.