Medication adherence and treatment-resistant hypertension: a review.
Medication adherence and treatment-resistant hypertension: a review.
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DOI：
10.7573/dic.212560
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发表时间：
2019-01-01
期刊：
影响因子：
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通讯作者：
Dasgupta, Indranil
中科院分区：
文献类型：
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作者：
Hameed, Mohammed Awais;Dasgupta, Indranil
不依从性是治疗失败和治疗耐药的常见原因。无论它是如何定义的，它都是慢性病管理中的一个主要问题。评估遵从性的方法有很多，每种方法都有自己的优点和缺点；然而，没有一种方法被认为是最好的。不依从性在高血压患者中很常见，而且在服用三种或更多降压药的血压未得到控制的患者中，这种情况占很大比例。随着评估依从性的新方法的发展，这些患者基于程序的治疗方案的可用性进一步揭示了这一重要问题。然而，对于不遵守的管理没有达成共识，这反映了造成这种情况的各种因素的复杂相互作用。
Nonadherence is a common reason for treatment failure and treatment resistance. No matter how it is defined, it is a major issue in the management of chronic illnesses. There are numerous methods to assess adherence, each with its own strengths and weaknesses; however, no single method is considered the best. Nonadherence is common in patients with hypertension, and it is present in a large proportion of patients with uncontrolled blood pressure taking three or more antihypertensive agents. Availability of procedure-based treatment options for these patients has shed further light on this important issue with development of new methods to assess adherence. There is, however, no consensus on the management of nonadherence, which reflects the complex interplay of factors responsible for it.