Increased Oral Porphyromonas gingivalis Prevalence in Cardiovascular Patients with Uncontrolled Diabetes Mellitus
Increased Oral Porphyromonas gingivalis Prevalence in Cardiovascular Patients with Uncontrolled Diabetes Mellitus
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DOI：
10.1536/ihj.17-480
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发表时间：
2018-07-01
影响因子：
1.5
通讯作者：
Isobe, Mitsuaki
中科院分区：
文献类型：
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作者：
Aoyama, Norio;Suzuki, Jun-ichi;Isobe, Mitsuaki
本研究的目的是确定牙周病细菌与心血管疾病（CVD）受试者糖尿病（DM）状态之间的相关性。糖尿病与牙周炎的进展有关。一些流行病学研究表明牙周炎可能是心血管疾病的危险因素。然而，没有研究比较控制良好和控制不良的糖尿病合并CVD患者的牙周状况。研究对象为控制良好（n = 73）或控制不良（n = 39）的糖尿病合并心血管疾病患者。进行血液检查和牙科临床测量，包括牙数、探诊袋深度、探诊出血（BOP）和临床附着水平（CAL）。评估牙周病细菌的存在。与对照组相比，未控制DM组的CAL和BOP率均有所恶化。我们发现，与控制良好的糖尿病患者相比，未控制的糖尿病患者的唾液牙龈pmphmonas计数增加。特异性牙周病细菌感染可能影响心血管疾病患者的糖尿病状况。
The aim of this study was to determine the correlation between periodontopathic bacteria and diabetes mellitus (DM) status in cardiovascular disease (CVD) subjects.DM is associated with the progression of periodontitis. Several epidemiological studies have suggested that periodontitis may be a risk factor for CVD. However, no study has compared the periodontal condition between well-controlled and poorly-controlled DM patients with CVD.The subjects were well-controlled (n = 73) or poorly-controlled (n = 39) DM patients with CVD. Blood examinations and dental clinical measurements, including number of teeth, probing pocket depth, bleeding on probing (BOP), and clinical attachment level (CAL) were performed. Periodontopathic bacterial existence was evaluated.Worsened CAL and BOP rate were detected in the uncontrolled DM group compared to the controlled group. We found increased salivary Pmphymmonas gingivalis counts in the uncontrolled DM group compared to well-controlled DM subjects.Specific periodontopathic bacterial infection may affect DM condition in CVD patients.