THE ANATOMICAL BASIS OF SOMATESTHETIC TEMPORAL DISCRIMINATION IN HUMANS
THE ANATOMICAL BASIS OF SOMATESTHETIC TEMPORAL DISCRIMINATION IN HUMANS
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DOI：
10.1136/jnnp.54.12.1077
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发表时间：
1991-12-01
影响因子：
11
通讯作者：
OBESO, JA
中科院分区：
文献类型：
--
作者：
LACRUZ, F;ARTIEDA, J;OBESO, JA
躯体审美时相辨别(STD)是指将施加于身体相同或不同部位的两个连续躯体审美刺激分开感知的能力。以不同时间间隔对食指施加成对电刺激，对84例正常人和51例脑局灶性病变患者的STD阈值进行了研究。初级躯体感觉皮质和内囊丘脑损害患者患侧STDT值异常。病变位于顶叶后皮质、尾状核头部、壳核、丘脑内侧核和豆状核，未引起感觉损害，但引起STDT异常。额叶、颞叶和枕叶皮质病变未引起STDT异常，但1例双侧辅助运动区(SMA)病变的STDT异常。这些结果表明，正常的两种躯体感觉刺激在时间上是分开的，不仅取决于躯体感觉通路和初级躯体感觉皮质的完整性，还取决于顶后皮质、SMA和皮质下结构(如纹状体和丘脑)的完整性。
Somaesthetic temporal discrimination (STD) is the ability to perceive as separate two successive somaesthetic stimuli applied to the same or different parts of the body. Paired electrical stimuli were applied to the index finger, using different time-intervals, to study the STD threshold (STDT) in 84 normal subjects and 51 patients with focal cerebral lesions. Abnormal STDT values were found on the affected side of patients with a lesion of the primary somatosensory cortex, and internal capsule-thalamus. Lesions which did not produce sensory impairment but caused abnormal STDT were located in the posterior parietal cortex, the head of the caudate nucleus, the putamen, the medial thalamus and the lenticular nucleus. Frontal, temporal and occipital cortex lesions did not produce any abnormality in the STDT, but one patient with a bilateral lesion of the supplementary motor area (SMA) had abnormal STDT. These results indicate that normal perception of two somaesthetic stimuli as separate in time depends not only upon the integrity of the somatosensory pathway and primary somaesthetic cortex, but also of the posterior parietal cortex, SMA and subcortical structures such as the striatum and thalamus.