Catalytic Asymmetric Dearomatizing Redox Cross Coupling of Ketones with Aryl Hydrazines Giving 1,4-Diketones
Catalytic Asymmetric Dearomatizing Redox Cross Coupling of Ketones with Aryl Hydrazines Giving 1,4-Diketones
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DOI：
10.1021/ja511200j
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发表时间：
2015-03-18
影响因子：
15
通讯作者：
List, Benjamin
中科院分区：
文献类型：
--
作者：
Huang, Shenlin;Koetzner, Lisa;List, Benjamin
在不对称Bronsted酸催化下，芳肼与酮反应生成高纯度的含全碳四元立构中心的1，4-二酮，实现了脱砷Redbox交叉偶联反应.
An asymmetric Bronsted acid catalyzed dearromating redbox cross coupling reaction has been realized, in which aryl hydrazines react with ketones to deliver 1,4-diketones, bearing an all-carbon, quarternary stereocenter in high enantiopurity.