Effects of multimodal fast-track surgery on liver transplantation outcomes
Effects of multimodal fast-track surgery on liver transplantation outcomes
复制标题
多模式快速通道手术对肝移植结局的影响
DOI：
10.1016/s1499-3872(17)60020-1
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发表时间：
2017-08-01
影响因子：
3.3
通讯作者：
Lu, Ling
中科院分区：
文献类型：
--
作者：
Rao, Jian-Hua;Zhang, Feng;Lu, Ling
背景：快速通道手术和术后恢复增强已被应用于许多外科手术；然而，关于肝移植后快速通道手术和术后恢复增强的数据有限。本研究旨在进行前瞻性研究，以确定快速通道手术对肝移植后预后的影响。方法：这是一项前瞻性、单盲、随机研究。将128例肝移植患者随机分为快速组(FT组，n=54)和常规组(NFT组，n=74)。主要终点是重症监护病房(ICU)住院日和住院日。次要终点：手术时间、无肝期时间、术中出血量、术中输血量、术后并发症、再住院率、术后死亡率。结果：两组术前人口学资料差异无统计学意义。中位ICU住院天数，FT组为2天(1~7天)，NFT组为5天(3~12天)(P
BACKGROUND: Fast-track surgery and enhanced recovery after surgery have been applied to many surgical procedures; however, data on fast-track surgery and enhanced recovery after surgery following liver transplantation is limited. This study aimed to conduct a prospective study to determine the effects of fast-track surgery on prognosis after liver transplantation.METHODS: This was a prospective, single-blinded, randomized study. One hundred twenty-eight patients undergoing liver transplantation were selected for the fast-track (FT group, n=54) or conventional process (NFT group, n=74). The primary endpoints were intensive care unit (ICU) stay and hospital stay. The secondary endpoints were as follows: operative time, anhepatic phase time, intraoperative blood loss, intraoperative blood transfusion volume, postoperative complications, readmission rate, and postoperative mortality.RESULTS: There was no significant difference in preoperative demographics between the two groups. The median ICU stay was 2 days (range 1-7 days) in the FT group and 5 days (range 3-12 days) in the NFT group (P