Urinary iodine percentile ranges in the United States.
Urinary iodine percentile ranges in the United States.
复制标题
美国尿碘百分位范围。
DOI：
10.1016/s0009-8981(02)00429-1
复制
发表时间：
2003
期刊：
影响因子：
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通讯作者：
Pezzullo,JohnC
中科院分区：
文献类型：
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作者：
Soldin,OffiePorat;Soldin,StevenJ;Pezzullo,JohnC
背景尿碘浓度可以反映膳食碘摄入量，因此尿碘浓度的测定可以反映人群的碘营养状况。目的确定美国正常人群尿碘（UI）百分位数范围。材料与方法第三次全国健康与营养调查（NationalHealthandNutritionExaminSurvey）（NHANES III）（1988-1994）数据库的平民，非制度化，碘充足的美国人口。计算6-89岁男性和女性尿碘和尿碘/肌酐比值（UI/Cr）（μg/g）的第2.5 - 97.5百分位数范围，每个年龄组分层。排除患有甲状腺肿或甲状腺疾病的受试者后，研究样本包括21，530例受试者; 10，439例男性和11，091例女性。对于育龄妇女（14-44岁），第2.5至97.5次尿碘浓度为1.8-65 μg/dl或36-539 μg/g肌酐。对于孕妇，范围为4.2-55 μg/dl或33-535 μg/g肌酐。
BackgroundThe status of iodine nutrition of a population can be determined by measurement of urinary iodine concentrations since it is thought to indicate dietary iodine intake. Normally, these results are compared to population-based criteria, since there are no reference ranges for urinary iodine.ObjectiveTo determine the percentile ranges for urinary iodide (UI) concentrations in normal individuals in the United States.Materials and methodsThe third National Health and Nutrition Examination Survey (NHANES III) (1988–1994) database of the civilian, non-institutionalized, iodine-sufficient US population was used. The 2.5th to 97.5th percentile ranges for urinary iodine and for urinary iodine per gram creatinine ratio (UI/Cr) (μg/g) were calculated for females and males, 6–89 years of age, each stratified by age groups.Results and conclusionsWe calculated the percentile ranges for urinary iodine. After exclusions of subjects with goiter or thyroid disease, the study sample included 21,530 subjects; 10,439 males and 11,091 females. For women of childbearing age (14–44 years), urinary iodine concentration 2.5th to 97.5th percentiles are 1.8–65 μg/dl or 36–539 μg/g creatinine. For pregnant women, the ranges are 4.2–55 μg/dl or 33–535 μg/g creatinine.