ISOLATION OF (10R,11R)-(+)-SQUALENE-10,11-EPOXIDE FROM THE RED ALGA LAURENCIA-OKAMURAI AND ITS ENANTIOSELECTIVE SYNTHESIS

ISOLATION OF (10R,11R)-(+)-SQUALENE-10,11-EPOXIDE FROM THE RED ALGA LAURENCIA-OKAMURAI AND ITS ENANTIOSELECTIVE SYNTHESIS
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DOI:
10.1016/s0040-4020(01)87533-5
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发表时间:
1986-01-01
期刊:
影响因子:
2.1
通讯作者:
YAMADA, K
YAMADA, K
中科院分区:
化学3区
文献类型:
--
作者:
KIGOSHI, H;OJIKA, M;YAMADA, K

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(10R, 11R)-(+)-Squalene-10,11-epoxide 1 has been isolated from the red alga Laurencia okamurai. On the basis of the spectral data and comparison to the racemic compound prepared from squalene, assignment of the planar structure was made. The enantioselective synthesis of 1 was performed, which determined the absolute stereochemistry of 1.