Scaling behaviour of hyaluronic acid in solution with mono- and divalent ions.
Scaling behaviour of hyaluronic acid in solution with mono- and divalent ions.
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DOI：
10.1002/masy.201050543
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发表时间：
2010-05
影响因子：
--
通讯作者：
Horkay, F
中科院分区：
文献类型：
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作者：
Geissler, E;Hecht, A-M;Horkay, F
一价和二价阳离子同时存在对聚电解质溶液热力学的影响尚未完全了解。在生理条件下，这些离子的组合影响生物聚合物系统中的结构形成。已知二价抗衡离子在聚合物主链周围形成紧密鞘，而单价离子分布在扩散云中。动态光散射测量的集体扩散系数D和渗透压缩性的半稀释透明质酸溶液中含有不同比例的钠和钙离子进行了比较与简单的ESTA模型。标度关系是根据聚合物浓度和添加的盐的离子强度J导出的。钠离子和钙离子作用的差异仅通过J.
The effect of the simultaneous presence of mono- and divalent cations on the thermodynamics of polyelectrolyte solutions is not fully understood. In physiological conditions, combinations of these ions affect structure formation in biopolymer systems. It is known that divalent counterions form a tight sheath around the polymer backbone, while monovalent ions are distributed in a diffuse cloud. Dynamic light scattering measurements of the collective diffusion coefficient D and the osmotic compressibility of semi-dilute hyaluronan solutions containing different ratios of sodium and calcium ions are compared with simple polyelectrolyte models. Scaling relationships are derived in terms of polymer concentration and ionic strength J of the added salt. Differences in the effects of sodium and calcium ions are expressed only through J.