Distinctions between manipulation and function knowledge of objects: evidence from functional magnetic resonance imaging
Distinctions between manipulation and function knowledge of objects: evidence from functional magnetic resonance imaging
复制标题
DOI：
10.1016/j.cogbrainres.2004.11.001
复制
发表时间：
2005-05-01
期刊：
影响因子：
--
通讯作者：
Detre, JA
中科院分区：
文献类型：
--
作者：
Boronat, CB;Buxbaum, LJ;Detre, JA
概念知识的一个突出的解释提出，信息分布在视觉、触觉、听觉、运动和言语陈述属性域上，其程度取决于当获得知识时这些特征被激活的程度[D. A. Allport，Distributed memory，modular subsystems and dysphagia，In：S.K.纽曼，R. Epstein（Eds.），当前吞咽困难的观点，丘吉尔利文斯通，爱丁堡，1985年，页。32-60]。一个推论是，当利用这种知识时（例如，为了回答问题），该分布式信息的特定方面根据手头任务的要求被重新激活[L. J. Buxbaum，E.M. Saffran，客体操作和客体功能的知识：在非行为主体和非行为主体中的分离。Brain and Language，82（2002）179-199; L.J. Buxbaum，T. Veramonti，M.F. Schwartz，失用症中的功能和操作工具知识：知道“为什么”但不知道“如何”，Neurocase，6（2000）83-97; W。西蒙斯湖，澳-地Barsalou，相似性拓扑原则：概念缺陷的验证理论，认知神经心理学，20（2003）451-186。这个解释预测，回答关于物体操作的问题应该激活先前被认为是参与物体使用的分布式感觉运动系统的组成部分的大脑区域，而回答关于物体功能（即它所服务的目的）的问题应该激活被认为是支持言语陈述特征的系统组成部分的区域。这些预测在功能性磁共振成像（fMRI）研究中进行了测试，其中15名参与者观看表示可操纵对象的图片或单词对，并确定对象是否被类似地操纵（M条件）或具有相同的功能（F条件）。与顶内沟接壤的左顶叶下叶的激活显著更大，更广泛，在M条件下与图片，并在较小程度上，单词。这些发现与该区域在熟练物体使用中的已知作用一致[K.M. Heilman，L. J. Gonzalez Rothi，失用症，In：K.M. Heilman，E. Valenstein（Eds.），《临床神经心理学》，牛津大学出版社，纽约，1993年，页。141-150]以及先前的fMRI结果[M.凯伦巴赫，M. Brett，K. Patterson，Actions Speak Louder Than Functions：the importance of manipulability and action in tool representation，Journal of Cognitive Neuroscience，15（2003）30-46]和脑损伤患者的行为发现[L. J. Buxbaum，E.M. Saffran，Knowledge of object manipulation and object function：dissociations in apraphilic and non-apraphilic subjects，Brain and Language，82（2002）179-199。没有大脑区域在F条件下比M条件下更活跃。这些数据表明，专门用于感觉运动功能的大脑区域是可操纵对象的分布式表示的关键组成部分。(c)2004 Elsevier B. V.保留所有权利。
A prominent account of conceptual knowledge proposes that information is distributed over visual, tactile, auditory, motor and verbal-declarative attribute domains to the degree to which these features were activated when the knowledge was acquired [D.A. Allport, Distributed memory, modular subsystems and dysphagia, In: S.K. Newman, R. Epstein (Eds.), Current perspectives in dysphagia, Churchill Livingstone, Edinburgh, 1985, pp. 32-60]. A corollary is that when drawing upon this knowledge (e.g., to answer questions), particular aspects of this distributed information is re-activated as a function of the requirements of the task at hand [L.J. Buxbaum, E.M. Saffran, Knowledge of object manipulation and object function: dissociations in apraxic and non-apraxic subjects. Brain and Language, 82 (2002) 179-199; L.J. Buxbaum, T. Veramonti, M.F. Schwartz, Function and manipulation tool knowledge in apraxia: knowing `what for' but not 'how', Neurocase, 6 (2000) 83-97; W. Simmons, L. Barsalou, The similarity-in-topography principle: Reconciling theories of conceptual deficits, Cognitive Neuropsychology, 20 (2003) 451-186]. This account predicts that answering questions about object manipulation should activate brain regions previously identified as components of the distributed sensory-motor system involved in object use, whereas answering questions about object function (that is, the purpose that it serves) should activate regions identified as components of the systems supporting verbal-declarative features. These predictions were tested in a functional magnetic resonance imaging (fMRI) study in which 15 participants viewed picture or word pairs denoting manipulable objects and determined whether the objects are manipulated similarly (M condition) or serve the same function (F condition). Significantly greater and more extensive activations in the left inferior parietal lobe bordering the intraparietal sulcus were seen in the M condition with pictures and, to a lesser degree, words. These findings are consistent with the known role of this region in skilled object use [K.M. Heilman, L.J. Gonzalez Rothi, Apraxia, In: K.M. Heilman, E. Valenstein (Eds.), Clinical Neuropsychology, Oxford University Press, New York, 1993, pp. 141-150] as well as previous fMRI results [M. Kellenbach, M. Brett, K. Patterson, Actions speak louder than functions: the importance of manipulability and action in tool representation, Journal of Cognitive Neuroscience, 15 (2003) 30-46] and behavioral findings in brain-lesion patients [L.J. Buxbaum, E.M. Saffran, Knowledge of object manipulation and object function: dissociations in apraxic and non-apraxic subjects, Brain and Language, 82 (2002) 179-199]. No brain regions were significantly more activated in the F than M condition. These data suggest that brain regions specialized for sensory-motor function are a critical component of distributed representations of manipulable objects. (c) 2004 Elsevier B.V. All rights reserved.