BRAIN-ABSCESS DUE TO GORDONA-TERRAE IN AN IMMUNOCOMPROMISED CHILD - CASE-REPORT AND REVIEW OF INFECTIONS CAUSED BY G-TERRAE
BRAIN-ABSCESS DUE TO GORDONA-TERRAE IN AN IMMUNOCOMPROMISED CHILD - CASE-REPORT AND REVIEW OF INFECTIONS CAUSED BY G-TERRAE
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DOI：
10.1093/clinids/19.2.258
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发表时间：
1994-08-01
影响因子：
11.8
通讯作者：
RAOULT, D
中科院分区：
文献类型：
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作者：
DRANCOURT, M;MCNEIL, MM;RAOULT, D
一名免疫功能低下男孩的原发性脑横纹肌样瘤的脑脓肿导致抗肿瘤化疗复杂化。通过颅内血肿手术穿刺获得的化脓性渗出物培养物产生革兰氏阳性微生物，通过常规生化分析最初鉴定为红球菌属物种；然而，随后通过核糖体 DNA 分析将该分离物鉴定为 Gordona terrae。据我们所知，这是第三例由土G. terrae引起的人类感染病例，也是第一例由这种生物体引起的脑脓肿病例。正如该病例所表明的，该物种可能会导致严重免疫功能低下的患者发生机会性侵袭性感染。应通过分子方法确认被认为是 G. terrae 的临床分离株的身份，直到获得更好的物种特异性表型标记。
A brain abscess complicated antineoplastic chemotherapy for a primary cerebral rhabdoid tumor in an immunocompromised boy. Culture of purulent exudate obtained by surgical puncture of an intracranial hematoma yielded a gram-positive microorganism initially identified as a Rhodococcus species by conventional biochemical analysis; however, the isolate was subsequently identified as Gordona terrae by ribosomal DNA analysis. To our knowledge, this is the third case of human infection caused by G. terrae and the first case of a brain abscess due to this organism. As this case demonstrates, this species may cause opportunistic invasive infection in severely immunocompromised patients. The identity of clinical isolates believed to be G. terrae should be confirmed by molecular methods until better species-specific phenotypic markers become available.