Qualitative investigation of the factors that generate ambivalent feelings in women who give birth after receiving negative results from non-invasive prenatal testing
Qualitative investigation of the factors that generate ambivalent feelings in women who give birth after receiving negative results from non-invasive prenatal testing
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DOI：
10.1186/s12884-020-2763-z
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发表时间：
2020-02-17
影响因子：
3.1
通讯作者：
Sago, Haruhiko
中科院分区：
文献类型：
--
作者：
Yotsumoto, Junko;Sekizawa, Akihiko;Sago, Haruhiko
在非侵入性产前基因检测（NIPT）中得到阴性结果的妇女可能会发现她们后来有一种复杂或矛盾的感觉，例如，接受NIPT的感觉和后悔进行测试的感觉。本研究旨在探讨在接受NIPT阴性结果后分娩的妇女中产生矛盾情绪的因素。方法对NIPT阴性女性进行问卷调查，并对1562名受访女性的矛盾情绪表达进行内容分析。使用N-Vivo软件包对问卷收集的定性数据进行分析。结果环境因素、遗传咨询相关因素和预期焦虑的增加影响孕妇的矛盾心理。此外，孕妇希望获得更多关于唐氏综合症患者的详细预后、与他们一起生活和/或终止妊娠的信息，假设他们可能是阳性的。结论影响女性矛盾心理的主要因素有三个。在遗传咨询中强调和讨论这些因素可能会解决这些矛盾，从而提高孕妇做出决定的质量。
Background Women who receive negative results from non-invasive prenatal genetic testing (NIPT) may find that they later have mixed or ambivalent feelings, for example, feelings of accepting NIPT and regretting undergoing the test. This study aimed to investigate the factors generating ambivalent feelings among women who gave birth after having received negative results from NIPT. Methods A questionnaire was sent to women who received a negative NIPT result, and a contents analysis was conducted focusing on ambivalent expressions for those 1562 women who responded the questionnaire. The qualitative data gathered from the questionnaire were analyzed using the N-Vivo software package. Results Environmental factors, genetic counseling-related factors, and increased anticipatory anxiety, affected the feeling of ambivalence among pregnant women. Furthermore, pregnant women desired more information regarding the detailed prognosis for individuals with Down syndrome and living with them and/or termination, assuming the possibility that they were positive. Conclusions Three major interrelated factors affected the feeling of ambivalence in women. Highlighting and discussing such factors during genetic counseling may resolve some of these ambivalences, thereby enhancing the quality of decisions made by pregnant women.