Beyond threat: Amygdala reactivity across multiple expressions of facial affect
Beyond threat: Amygdala reactivity across multiple expressions of facial affect
复制标题
DOI：
10.1016/j.neuroimage.2005.11.003
复制
发表时间：
2006-05-01
期刊：
影响因子：
5.7
通讯作者：
Phan, K. Luan
中科院分区：
文献类型：
--
作者：
Fitzgerald, Daniel A.;Angstadt, Mike;Phan, K. Luan
杏仁核一直被认为是处理面部情感表现的关键神经基质。最近来自人类病变和功能性神经成像研究的证据已经开始挑战杏仁核是为威胁信号（恐惧/愤怒）保留的概念。我们进行了一项4 T fMRI研究，其中20名受试者观看了一组显示6种不同面部表情（恐惧，厌恶，愤怒，悲伤，中性，快乐）的当代照片，同时执行一项具有最小认知需求的任务。在所有受试者中，左杏仁核分别被每种面部条件激活，它的反应对任何特定的情绪类别都没有选择性。这些结果挑战了杏仁核在处理某些情绪方面具有特殊作用的观点，并表明杏仁核在处理来自面部的显著信息方面可能具有更通用的功能。(c)2005年爱思唯尔公司All rights reserved.
The amygdala has been consistently isolated as a key neural substrate for processing facial displays of affect. Recent evidence from human lesion and functional neuroimaging studies have begun to challenge the notion that the amygdala is reserved for signals of threat (fear/anger). We performed a 4 T fMRI study in which 20 subjects viewed a contemporary set of photographs displaying 6 different facial expressions (fearful, disgusted, angry, sad, neutral, happy) while performing a task with minimal cognitive demand. Across subjects, the left amygdala was activated by each face condition separately, and its response was not selective for any particular emotion category. These results challenge the notion that the amygdala has a specialized role in processing certain emotions and suggest that the amygdala may have a more general-purpose function in processing salient information from faces. (c) 2005 Elsevier Inc. All rights reserved.