Inhaled synthetic cannabinoids laced with long-acting anticoagulant rodenticides: A clear and present worldwide danger.
Inhaled synthetic cannabinoids laced with long-acting anticoagulant rodenticides: A clear and present worldwide danger.
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吸入的合成大麻素与长效抗凝啮齿动物相处：一种清晰而当前的危险。
DOI：
10.1080/24734306.2022.2025690
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发表时间：
2022
影响因子：
--
通讯作者：
Rubinstein, Israel
中科院分区：
文献类型：
--
作者：
Feinstein, Douglas L.;Hafner, John;van Breemen, Richard;Rubinstein, Israel
douglas L. Feinstein a、b、John hafner c、richard van Breemen d 和 israel rubinstein a、e a 研究和医疗服务，Jesse Brown Va 医疗中心，美国伊利诺伊州芝加哥市； b 伊利诺伊大学芝加哥医学院麻醉学系，美国伊利诺伊州芝加哥； c 伊利诺伊大学皮奥里亚医学院急诊医学系，美国伊利诺伊州皮奥里亚；美国俄勒冈州科瓦利斯市俄勒冈州立大学 dlinus Pauling 研究所；美国伊利诺伊州芝加哥芝加哥伊利诺伊大学医学院医学系致编辑：2016 年，我们撰写了一篇前瞻性评论，内容涉及美国人可能恶意接触第二代长效（数月）抗凝血灭鼠剂 (LAAR)，如溴鼠灵、溴敌隆和苯芬那威，以及制定有效对策以减轻其长期毒性作用的必要性[1]。我们的预测在 2018 年 3 月实现，当时美国有 400 多人因吸入含有 LAAR 的合成大麻素而中毒，并出现严重凝血功能障碍和出血，据报道有 11 人死亡 [2, 3]。 2021 年 9 月，以色列报告了类似的疫情，有 95 人因吸入含有溴化灵的合成大麻素而因严重凝血功能障碍和出血而入院治疗，迄今报告有 3 人死亡 [4]（Lurie Y. 个人通讯）。 2021 年 12 月，佛罗里达州希尔斯伯勒县有 45 名无家可归者因吸入含有溴敌螨的合成大麻素而因严重凝血功能障碍和出血而住院，迄今为止已报告 2 人死亡 [5]（Mulay PR. 个人通讯）。
douglas L. Feinstein a, b, John hafner c, richard van Breemen d and israel rubinstein a, e aResearch and medical services, Jesse Brown Va medical center, chicago, il, usa; bDepartment of anesthesiology, university of illinois college of medicine at chicago, chicago, il, usa; cDepartment of Emergency medicine, university of illinois college of medicine at Peoria, Peoria, il, usa; dlinus Pauling institute, oregon state university, corvallis, oR, usa; eDepartment of medicine, university of illinois college of medicine at chicago, chicago, il, usaTo the Editor, In 2016 we wrote a forward looking commentary about possible malicious exposure of people in the US to second generation, long-acting (months) anticoagulant rodenticides (LAAR’s), such as brodifacoum, bromadiolone and difenacoum, and the need to develop effective countermeasures to mitigate their prolonged toxic effects [1]. Our prediction materialized in March 2018, when more than 400 people in the US were poisoned and developed severe coagulopathy and bleeding after inhaling synthetic cannabinoids laced with LAAR’s with 11 reported deaths [2, 3]. In September 2021 a similar outbreak was reported from Israel where 95 people who inhaled synthetic cannabinoids laced with brodifacoum have been hospitalized with severe coagulopathy and bleeding with 3 deaths reported so far [4](Lurie Y. Personal communication). During December 2021, 45 mostly homeless individuals in Hillsborough County, Florida were hospitalized with severe coagulopathy and bleeding after inhaling synthetic cannabinoids laced with brodifacoum with 2 deaths reported so far [5](Mulay PR. Personal Communication).
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影响因子：
--
作者：
Nosal DG;van Breemen RB;Haffner JW;Rubinstein I;Feinstein DL
通讯作者：
Feinstein DL
影响因子：
158.5
作者：
Kelkar, Amar H.;Smith, Nichole A.;Roberts, Jonathan C.
通讯作者：
Roberts, Jonathan C.
影响因子：
3.3
作者：
Devgun, Jason M.;Rasin, Arkady;Aks, Steven E.
通讯作者：
Aks, Steven E.
影响因子：
5
作者：
Tole, Mateo;LaBedz, Stephanie;Rubinstein, Israel
通讯作者：
Rubinstein, Israel
影响因子：
--
作者：
van Breemen RB;Hafner JW;Nosal DG;Feinstein DL;Rubinstein I
通讯作者：
Rubinstein I