Dementia, Mild Cognitive Impairment and Quantitative EEG in Patients With Parkinson's Disease
Dementia, Mild Cognitive Impairment and Quantitative EEG in Patients With Parkinson's Disease
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DOI：
10.1177/155005940904000309
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发表时间：
2009-07-01
影响因子：
2
通讯作者：
Bossoni, A. S.
中科院分区：
文献类型：
--
作者：
Fonseca, L. C.;Tedrus, G. M. A. S.;Bossoni, A. S.
这项研究的目的是评估定量脑电图（QEEG）变化与认知障碍（轻度认知障碍或痴呆症）与帕金森氏病（PD）的运动障碍阶段（PD）。 10,0）和26名正常受试者（年龄= 68.4 +/- 4.7）使用神经评估，修改后的Hoehn和Yahr（HY）量表（葡萄牙语版本）（Cerad神经心理电池的葡萄牙版本）（为建立一个注册表建立注册表的葡萄牙语版本）阿尔茨海默氏病）结合了静止时的绝对和相对带振幅的小精神状态检查，临床痴呆评级和脑电图分析。比较了四组：三个患有PD（7例痴呆患者，10例患者认知障碍患者，没有认知障碍），对照组进行了。 QEEG异常与PD患者的轻度认知障碍或痴呆症的发生基本上有关。在痴呆症研究中，痴呆症的绝对障碍或痴呆症的绝对和相对后theta幅度有所增加，并且在痴呆症研究中的绝对绝对和相对三角幅度增加，这表明QEEG是评估认知方面的生理工具。 PD。
The objective of this study was to evaluate relationships between quantitative EEG (qEEG) changes and cognitive disturbance (mild cognitive impairment or dementia) and the motor disturbance stage in Parkinson's disease (PD).Thirty-two PD patients (age=67.2 +/- 10,0) and 26 normal subjects (age=68.4 +/- 4.7) were assessed using a neurological evaluation, modified Hoehn and Yahr (HY) scale for PD, a Portuguese version of the CERAD neuropsychological battery (consortium to establish a registry for Alzheimer's disease) incorporating the Mini-mental Status Examination, Clinical Dementia Rating and an EEG analysis of absolute and relative band amplitude at rest. Four groups were compared: three with PD (7 patients with dementia, 10 with mild cognitive impairment and 15 with no cognitive disturbances) and the control group.The qEEG showed no significant differences between the control group and PD patients without cognitive disturbance. Abnormalities on the qEEG were essentially associated with the occurrence of mild cognitive impairment or dementia in patients with PD. There was an increase in the absolute and relative posterior theta amplitude in the groups with mild cognitive impairment or dementia and of the posterior absolute and relative delta amplitude in the group with dementiaThis study suggested qEEG as a possible physiological tool in the assessment of cognitive aspects in PD.