Racial differences in survival from breast cancer.

Racial differences in survival from breast cancer.
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乳腺癌生存率存在种族差异。

DOI:
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发表时间:
1995
期刊:
Journal of the American Medical Association (JAMA)
影响因子:
--
通讯作者:
S. Joslyn
S. Joslyn
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文献类型:
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作者:
S. Joslyn

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致《编辑》。-我怀着极大的兴趣阅读了埃利博士和他的同事们1关于乳腺癌存活率的种族差异的文章。这项研究是确定乳腺癌存活率中种族差异性质的最完整、设计和进行得最好的研究之一。数据收集方法、混杂因素的管理和统计分析都是例外的。关于白人受试者与黑人受试者在年龄上的频率匹配问题,我有一个问题要问作者。通过对这一重要变量的匹配(过度匹配),排除了将年龄作为生存因素的可能比较。几项研究2-4表明,与白人女性相比,非裔美国女性的确诊年龄明显更低,存活率也更低,这可能表明这两组肿瘤之间的基本生物学差异。年龄可能是种族间存活率差异的一个主要解释变量,除了或取代在
To the Editor. —I read with great interest the article by Dr Eley and colleagues 1 regarding racial differences in survival from breast cancer. This investigation is one of the most complete, well-designed, and well-conducted studies to determine the nature of racial differences in breast cancer survival. The data-collection methods, management of confounding factors, and statistical analyses were exceptional. I have a question for the authors regarding frequency matching of white subjects to black subjects by age. By matching (overmatching) on this important variable, possible comparisons of age as a factor in survival were eliminated. Several studies 2-4 have indicated significantly younger age at diagnosis in African-American women compared with white women, along with poorer survival rates, which may indicate basic biological differences between tumors in these two groups. Age may be a major explanatory variable in survival differences between races, in addition to or instead of those found in
DOI: 10.1126/science.7545954
发表时间: 1994-10-07
期刊: SCIENCE
影响因子: 56.9
作者:
MIKI, Y;SWENSEN, J;SKOLNICK, MH
通讯作者: SKOLNICK, MH