Chronic Mountain Sickness: A Pulmonary Vascular Disease?

Chronic Mountain Sickness: A Pulmonary Vascular Disease?
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慢性高山病:一种肺血管疾病?

DOI:
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发表时间:
1982
期刊:
影响因子:
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通讯作者:
S. Recavarren
S. Recavarren
中科院分区:
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文献类型:
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作者:
J. Cruz;S. Recavarren

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1928年,卡洛斯·蒙格(25岁)首次报道了慢性高原病(CMS),即“慢性高山病”、“艾尔图拉血症”或“蒙格病”。从那时起,关于这种疾病的概念和知识已经演变(3,17,19,26,27,29,32,40,42),以至于人们对这种疾病是否真的存在提出了怀疑,这种怀疑是由于缺乏解剖学证据(15)。大多数CMS患者是高海拔(3000米以上)的终身居民。他们可能没有症状,生活正常。有症状的患者可能会主诉视力模糊、头痛、呼吸困难、失眠和感觉异常。体格检查可发现手指有棍棒状,巩膜充血,粘膜发紫。在极端情况下,可以看到右心衰竭的症状和体征(26,29,32)。
Chronic mountain sickness (CMS), “soroche cronico,” “eritremia de la altura,” or “Monge’s disease” was first reported in 1928 by Carlos Monge (25). Since then, concepts of and knowledge about this disease have evolved (3,17,19,26,27,29, 32,40,42) up to the point at which doubts have been raised as to whether this disease really exists, the doubt due to the lack of anatomical evidence (15). Most people with CMS are lifelong residents at high altitude (above 3000 m). They may be asymptomatic and live normally. Symptomatic patients may complain of blurred vision, headache, dyspnea, insomnia, and paresthesias. Physical examination may reveal clubbing of fingers, congestion of sclerae, and mucosa with cyanosis. In extreme cases, symptoms and signs of right-heart failure are seen (26, 29,32).