Corticomotor excitability of wrist flexor and extensor muscles during active and passive movement
Corticomotor excitability of wrist flexor and extensor muscles during active and passive movement
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DOI：
10.1016/j.humov.2010.03.003
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发表时间：
2010-08-01
影响因子：
2.1
通讯作者：
Thickbroom, Gary
中科院分区：
文献类型：
--
作者：
Chye, Lilian;Nosaka, Ken;Thickbroom, Gary
皮质脊髓投射到上肢和下肢的兴奋性在自愿和被动运动过程中不断调制;然而，在可比运动期间的直接比较尚未报道。在本研究中，我们使用经颅磁刺激（TMS）比较皮质运动的兴奋性，前臂的桡侧腕伸肌和腕屈肌（ECR/FCR）肌肉在自愿的有节奏的手腕运动（通过45度的范围），在一个匹配的（范围和节奏）被动运动的手腕，而手腕是静止的（在中程）。当腕关节处于中立位时输送TMS。与被动和主动运动，FCR和ECR，corticomotor兴奋性降低延长相对于缩短阶段的运动。随着主动运动，这种模式得到维持，并叠加在两块肌肉的兴奋性总体增加上，ECR的兴奋性更大。结果有利于一个共同的模式的兴奋性变化共享的伸肌和屈肌肌肉，因为他们经历延长和缩短，这可能是由传入输入介导的被动和主动运动。这与主动运动相关的兴奋性的总体增加相结合，伸肌的兴奋性更大，这可能是由于这些肌肉的皮质运动投射强度的差异。(C)2010爱思唯尔有限公司版权所有。
The excitability of the corticospinal projection to upper and lower limbs is constantly modulated during voluntary and passive movement; however a direct comparison during a comparable movement has not been reported. In the present study we used transcranial magnetic stimulation (TMS) to compare corticomotor excitability to the extensor and flexor carpi radialis (ECR/FCR) muscles of the forearm during voluntary rhythmic wrist movement (through 45 degrees of range), during a matched (for range and rhythm) passive movement of the wrist, and while the wrist was stationary (in mid-range). TMS was delivered when the wrist was in the neutral position. With passive and active movement, and for both FCR and ECR, corticomotor excitability was reduced during lengthening relative to shortening phases of movement. With active movement, this pattern was maintained and superimposed on an overall increase in excitability to both muscles that was greater for the ECR. The results favor a common pattern of excitability changes shared by extensor and flexor muscles as they undergo lengthening and shortening, which may be mediated by afferent input during both passive and active movement. This is combined with an overall increase in excitability associated with active movement that is greater for extensor muscles perhaps due to differences in the strength of the corticomotor projection to these muscles. (C) 2010 Elsevier B.V. All rights reserved.