Produce, carry/position, and connect: morphogenesis using rigid materials
Produce, carry/position, and connect: morphogenesis using rigid materials
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生产、携带/定位和连接：使用刚性材料的形态发生
DOI：
10.1016/j.gde.2019.08.001
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发表时间：
2019
影响因子：
4
通讯作者：
Funayama Noriko
中科院分区：
文献类型：
--
作者：
越阪部晃永;山﨑慈恵;田中祐梨子;Bhagyshree Jamge;Zdravko Lorkovic;Frederic Berger;角谷徹仁;Funayama Noriko
动物的形态发生可以概括为大量细胞的重新配置。虽然细胞外基质，包括刚性骨骼元素，如软骨/骨和外骨骼，在形态发生中具有重要作用，它们也被分泌在原位积累的细胞或上皮细胞。相比之下，最近的研究海绵（多孔动物）的骨架建设阐明了一个概念上不同的机制，其中细胞操纵相当精细的刚性材料（骨针），形成更大的结构形态。在这里，使用钙质针状体或硅质针状体的两种不同类型的海绵骨架形成在刚性材料的生产及其在骨架中的使用的概念方面进行了比较。比较突出了它们形成海绵骨架的不同策略的优点。
Animal morphogenesis can be summarized as a reconfiguration of a mass of cells. Although extracellular matrices that include rigid skeletal elements, such as cartilage/bones and exoskeletons, have important roles in morphogenesis, they are also secretedin situby accumulated cells or epithelial cells. In contrast, recent studies of the skeleton construction of sponges (Porifera) illuminate a conceptually different mechanism of morphogenesis in which cells manipulate rather fine rigid materials (spicules) to form larger structures. Here, two different types of sponge skeleton formation using calcareous spicules or siliceous spicules are compared with regard to the concept of the production of rigid materials and their use in skeletons. The comparison highlights the advantages of their different strategies of forming sponge skeletons.