REDUCTION OF BRAIN SPECIFIC-GRAVITY IN MICE PRENATALLY EXPOSED TO TRICHLOROETHYLENE

REDUCTION OF BRAIN SPECIFIC-GRAVITY IN MICE PRENATALLY EXPOSED TO TRICHLOROETHYLENE
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DOI:
10.1016/0378-4274(84)90130-9
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发表时间:
1984-01-01
期刊:
影响因子:
3.5
通讯作者:
JOHANSSON, BB
JOHANSSON, BB
中科院分区:
医学3区
文献类型:
--
作者:
WESTERGREN, I;KJELLSTRAND, P;JOHANSSON, BB

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大脑的比重在出生时较低,并随着髓鞘形成和成熟而增加。交配前后暴露于三氯乙烯 (TCE) 的小鼠所产下的小鼠的大脑比重在出生时、10 日龄和 20-22 天时显着低于未暴露于三氯乙烯 (TCE) 的小鼠的小鼠。这可能表明成熟延迟。 1 个月龄时,暴露组和未暴露组之间没有观察到显着差异。
The specific gravity of the brain is low at birth and increases in parallel with myelination and maturation. The brain specific gravity of litters from mice exposed to trichloroethylene (TCE) before and after mating was significantly lower than in litters from unexposed parents at birth and at the age of 10 and 20-22 days. This might have indicated a delayed maturation. No significant difference between exposed and unexposed litters was observed at the age of 1 mo.