Use of a species-specific antibody for demonstrating mouse neurons transplanted to rat brains.
Use of a species-specific antibody for demonstrating mouse neurons transplanted to rat brains.
复制标题
使用物种特异性抗体来演示小鼠神经元移植到大鼠大脑中。
DOI：
10.1016/0304-3940(85)90428-8
复制
发表时间：
1985
影响因子：
2.5
通讯作者：
Lagenaur,CF
中科院分区：
文献类型：
--
作者：
Lund,RD;Chang,FL;Hankin,MH;Lagenaur,CF
一种特异于小鼠中枢神经系统神经元的细胞表面单克隆抗体被用于鉴定移植到新生大鼠脑中的小鼠组织。神经元胞体和突起在移植物中被染色。未成熟的轴突被染色，从移植物中生长到宿主脑中;在成熟的脑中，无髓鞘轴突和终末神经丛被证明。该技术允许对移植物-宿主相互作用进行各种研究，特别是在两者密切相关的情况下。
A cell surface monoclonal antibody specific for mouse central nervous system neurons was used to identify mouse tissue transplanted to neonatal rat brains. Neuronal cell bodies and processes were stained in the transplants. Immature axons were stained growing out of the transplants into the host brain; and in mature brains unmyelinated axons and terminal plexuses were demonstrated. The technique allows a variety of studies to be performed on transplant-host interactions, especially in circumstances where the two are closely apposed.