Contrast-enhanced ultrasound may distinguish gallbladder adenoma from cholesterol polyps: a prospective case-control study
Contrast-enhanced ultrasound may distinguish gallbladder adenoma from cholesterol polyps: a prospective case-control study
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DOI：
10.1007/s00261-015-0485-x
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发表时间：
2015-10-01
影响因子：
--
通讯作者：
Li, Hong-tian
中科院分区：
文献类型：
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作者：
Fei, Xiang;Lu, Wen-Ping;Li, Hong-tian
本研究的目的是通过对比增强超声（CEUS）发现与胆囊（GB）腺瘤和胆固醇息肉相关的独立危险因素。2010年1月至2014年9月，共纳入122例连续行胆囊切除术的GB息肉样病变患者。胆囊切除术前，每位患者均行常规超声和超声造影检查，并记录所有影像学特征。根据病理结果将患者分为腺瘤组和胆固醇息肉组。两组之间的所有图像特征进行统计学比较。两组患者年龄、病变大小、回声强度、病变血管分布差异均有统计学意义（P < 0.05）。两组间茎宽和强化强度差异有统计学意义（P < 0.05）。多因素logistic回归分析证实强化强度、病变柄、血管状况是与GB腺瘤相关的独立危险因素（P < 0.05）。超声造影可为区分腺瘤和胆固醇息肉提供有用的信息。胆囊息肉病变的治疗方法可能受益于超声造影作为常规影像学检查，特别是在息肉大于1cm的情况下。
The aim of this study was to find the independent risk factors related with gallbladder (GB) adenoma compared to cholesterol polyp by contrast-enhanced ultrasound (CEUS).Between January 2010 and September 2014, a total of 122 consecutive patients undergoing cholecystectomy for GB polypoid lesions were enrolled. Before cholecystectomy, each patient underwent conventional US and CEUS examination and all image features were documented. The patients were divided into adenoma group and cholesterol polyp group according to the pathological findings. All the image features between two groups were statistically compared.There were differences in patient age, lesion size, echogenicity, and vascularity of lesion between two groups (P < 0.05). There were differences in stalk width and enhancement intensity between the two groups (P < 0.05). Multiple logistic regression analysis proved that enhancement intensity, stalk of lesion, and vascularity were the independent risk factors related with GB adenoma (P < 0.05).CEUS could offer useful information to distinguish adenoma from cholesterol polyp. The treatment algorithm for gallbladder polyp lesions would likely benefit from CEUS as a routine imaging investigation, especially in cases where the polyp is larger than 1 cm.