Lymphocytic interstitial pneumonia.
Lymphocytic interstitial pneumonia.
复制标题
淋巴细胞性间质性肺炎。
DOI：
10.1016/s0031-3955(16)38044-0
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发表时间：
1991
影响因子：
2.6
通讯作者：
Pitt,J
中科院分区：
文献类型：
--
作者：
Pitt,J
淋巴细胞性间质性肺炎目前是一种病理诊断。在儿童慢性间质性肺炎伴淋巴细胞增多、高球蛋白血症、淋巴结病或腮腺肿大的情况下，诊断通常是临床推测的。目前只有通过肺活检才能明确诊断。发病机制的模型包括免疫系统的非特异性刺激、HIV特异性刺激或EBV和HIV之间的协同作用。治疗包括氧气和支气管扩张剂（根据需要）。齐多夫定和类固醇在治疗LIP中的作用仍有待确定。
Lymphocytic interstitial pneumonia is at present a pathologic diagnosis. In the setting of a chronic interstitial pneumonia in a child with lymphocytosis, hyperglobulinemia, and lymphadenopathy or parotid enlargement, the diagnosis is often clinically presumed. At present the diagnosis can be established firmly only by lung biopsy. Models of pathogenesis include nonspecific stimulation of the immune system, HIV-specific stimulation, or synergy between EBV and HIV. Treatment includes oxygen and bronchodilators as needed. The role of zidovudine and of steroids in the management of LIP remains to be determined.