Laser-induced forward transfer of liquids:: Study of the droplet ejection process
Laser-induced forward transfer of liquids:: Study of the droplet ejection process
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DOI：
10.1063/1.2191569
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发表时间：
2006-04-15
影响因子：
3.2
通讯作者：
Morenza, J. L.
中科院分区：
文献类型：
--
作者：
Colina, M.;Duocastella, M.;Morenza, J. L.
激光诱导正向传输(LIFT)是一种激光直写技术，它提供了从固体或液体状态的各种材料(如导体、电介质和溶液中的生物分子)打印出高空间分辨率图案的可能性。这种多功能性使Lift成为生物分子微阵列快速成型的基于光刻的工艺的一种非常有前途的替代方案。在这里，我们研究了通过提升适合于微阵列制备的溶液的液滴的转移过程。系统地改变了激光脉冲能量和光束大小，并评价了激光脉冲能量和光束大小对转移液滴的影响。通过改变这些参数，可以获得沉积液滴显示最佳特征的受控转移。此外，转移液滴体积与激光脉冲能量呈线性关系。这种依赖关系允许确定阈值能量密度值，而与激光聚焦条件无关，激光聚焦条件作为转移发生的必要条件。对于不同的光束维度，采用不同的总能量阈值，给出了相应的充分条件。发现阈值能量密度是决定每个激光脉冲传输液体的量的尺寸参数，并且在传输过程中没有由于液体汽化而导致物质的大量损失。(C)2006年美国物理研究所。
Laser-induced forward transfer (LIFT) is a laser direct-write technique that offers the possibility of printing patterns with a high spatial resolution from a wide range of materials in a solid or liquid state, such as conductors, dielectrics, and biomolecules in solution. This versatility has made LIFT a very promising alternative to lithography-based processes for the rapid prototyping of biomolecule microarrays. Here, we study the transfer process through the LIFT of droplets of a solution suitable for microarray preparation. The laser pulse energy and beam size were systematically varied, and the effect on the transferred droplets was evaluated. Controlled transfers in which the deposited droplets displayed optimal features could be obtained by varying these parameters. In addition, the transferred droplet volume displayed a linear dependence on the laser pulse energy. This dependence allowed determining a threshold energy density value, independent of the laser focusing conditions, which acted as necessary conditions for the transfer to occur. The corresponding sufficient condition was given by a different total energy threshold for each laser beam dimension. The threshold energy density was found to be the dimensional parameter that determined the amount of the transferred liquid per laser pulse, and there was no substantial loss of material due to liquid vaporization during the transfer. (C) 2006 American Institute of Physics.