Quantum yield enhancement of firefly bioluminescence with biomolecular condensates

Quantum yield enhancement of firefly bioluminescence with biomolecular condensates
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DOI:
10.1039/d2cc04919h
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发表时间:
2022-10-28
影响因子:
4.9
通讯作者:
Kurita, Ryoji
Kurita, Ryoji
中科院分区:
化学2区
文献类型:
--
作者:
Nishihara, Ryo;Kihara, Yoshiki;Kurita, Ryoji

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萤火虫的酶促发光反应在含有带正电肽和ATP的生物分子凝聚物的存在下被加速。我们发现这种加速是由反应元素的富集、局部pH的变化和抑制性中间解离的促进引起的,使生物发光量子产率提高了约10%。
The enzymatic luminescence reactions of fireflies are accelerated in the presence of biomolecular condensates comprising a positively charged peptide and ATP. We revealed that this acceleration is caused by the enrichment of reaction elements, local pH changes, and promotion of inhibitory intermediate dissociation, improving the bioluminescence quantum yield by approximately 10%.