Hospital Usage of Parenteral Antimicrobial Agents: A Gradated Utilization Review and Cost Containment Program
Hospital Usage of Parenteral Antimicrobial Agents: A Gradated Utilization Review and Cost Containment Program
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医院使用肠外抗菌药物：分级使用审查和成本控制计划
DOI：
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发表时间：
1985
期刊：
影响因子：
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通讯作者：
L. L. Pelletier
中科院分区：
文献类型：
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作者：
L. L. Pelletier
在没有有效的抗菌药物审查和控制程序的医院中，40%至60%的抗菌药物是不需要的。在医院过度使用抗微生物药物会促进耐药菌患者的定植，不必要地使他们面临药物不良反应的风险，并增加护理费用。提出了一种分级抗菌药物使用审查方案，确定医院使用情况，制定适当的具有成本效益的药物管理指南，提供几种实施方案，并监测结果，以便根据具体情况修改措施。所使用的技术是目前用于评估医院感染的基本流行病学措施。
Abstract Forty percent to 60% of antimicrobial agents administered in hospitals without effective antimicrobial review and control programs are not needed. Excessive use of antimicrobial agents in the hospital promotes colonization of patients with resistant organisms, needlessly exposes them to the risk of an adverse drug reaction, and increases the cost of care. A gradated antimicrobial utilization review program is presented that determines hospital usage, develops guidelines for appropriate cost-effective drug administration, provides several options for implementation, and monitors outcome so that measures can be modified for specific situations. The techniques used are basic epidemiologic measures currently used to assess hospital infections.