Effectiveness of an intervention to prevent frailty in pre-frail community-dwelling older people consulting in primary care: a randomised controlled trial
Effectiveness of an intervention to prevent frailty in pre-frail community-dwelling older people consulting in primary care: a randomised controlled trial
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DOI：
10.1093/ageing/afw242
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发表时间：
2017-05-01
期刊：
影响因子：
6.7
通讯作者：
Papiol, M.
中科院分区：
文献类型：
--
作者：
Serra-Prat, M.;Sist, X.;Papiol, M.
背景：关于干预措施预防虚弱的有效性的证据是scarce.to评估干预措施在预防虚弱前老年人虚弱进展中的作用。两个平行组的对照试验。社区居住的体弱前老年人（70年千分之一）初级保健咨询。（并在出现营养风险时转到营养科进行常规护理）以及一项体育活动计划，包括有氧运动和一套综合强化、平衡和协调运动。在12个月随访时的功能能力（Barthel指数）、福尔斯和营养状况（简易营养评估）months.one招募并随机分配了172名参与者（平均年龄：78.3岁; Fried标准的平均数量：1.45）。39名参与者（22.6%）在研究期间退出。随访时，干预组和对照组分别有4.9%和15.3%的患者发展为虚弱，粗比值比（OR）为0.29（95%置信区间[CI]：0.08-1.08; P = 0.052）和调整后的（根据年龄、性别和合并症数量）OR为0.19（95% CI：0.04-0.95; P = 0.044）。干预组每天户外步行时间高于对照组（0.97 vs 0.73; P = 0.019），但在肌力、步速等功能指标上无差异。针对社区居住的体弱前老年人，以体育锻炼和维持良好营养状况为重点的干预可能有效预防体弱。
Background: evidence on the effectiveness of interventions to prevent frailty is scarce.to assess the effect of an intervention in preventing frailty progression in pre-frail older people.a randomised, open label, controlled trial with two parallel arms.community-dwelling pre-frail older people (a parts per thousand 70 years) consulting in primary care.nutritional assessment (and derivation to a Nutritional Unit for usual care in the event of nutritional risk) and a physical activity programme including aerobic exercise and a set of mixed strengthening, balance and coordination exercisespatients receiving the usual care.prevalence of frailty (Fried criteria) at 12 months.functional capacity (Barthel index), falls and nutritional status (Short-Form Mini Nutritional Assessment) on follow-up at 12 months.one hundred and seventy-two participants were recruited and randomised (mean age: 78.3 years; mean number of Fried criteria: 1.45). Thirty-nine participants (22.6%) were dropped out during the study. At follow-up, 4.9% of the intervention group and 15.3% of the control group had evolved to frailty, for a crude odds ratio (OR) of 0.29 (95% confidence interval [CI]: 0.08-1.08; P = 0.052) and an adjusted (by age, gender and number of co-morbidities) OR of 0.19 (95% CI: 0.04-0.95; P = 0.044). Intervention group showed a higher outdoors walking hour per day (0.97 versus 0.73; P = 0.019) but no difference was observed in muscle strength, gait speed or other functional indicators.an intervention focused on physical exercise and maintaining good nutritional status may be effective in preventing frailty in community-dwelling pre-frail older individuals.