Phenformin: AMP(K)ed for Potential Repurposing.
Phenformin: AMP(K)ed for Potential Repurposing.
复制标题
DOI：
10.1016/j.jid.2020.06.008
复制
发表时间：
2021-01
期刊：
影响因子：
--
通讯作者：
J. Jung;W. Bollag
中科院分区：
文献类型：
--
作者：
J. Jung;W. Bollag
The results in the article by Zhou et al. (2020) demonstrate that the antidiabetic drug phenformin inhibits skin tumor growth and promotes keratinocyte differentiation, and an underlying mechanism is also defined. In this commentary, additional potential mechanisms through which phenformin may exert its antitumorigenic effect are described. Thus, the proposed repurposing of phenformin to treat skin cancer has merit.
