Abnormalities of the spatiotemporal characteristics of gait at the onset of freezing in Parkinson's disease
Abnormalities of the spatiotemporal characteristics of gait at the onset of freezing in Parkinson's disease
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DOI：
10.1002/mds.1206
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发表时间：
2001-11-01
影响因子：
8.6
通讯作者：
Broens-Kaucsik, E
中科院分区：
文献类型：
--
作者：
Nieuwboer, A;Dom, R;Broens-Kaucsik, E
我们调查了时空变量的步态导致冻结。对14例帕金森病患者在停药期进行步态分析。一个计算机化的三维步态分析系统被用来珍惜步行模式。经过几次试验正常的墙壁与自愿停止。在人行道上使用分散注意力的动作和障碍物，以引起冻结或狂热。步态变量的正常（关闭阶段），festinating，prestop，和prefreezing的步伐进行了分析，重复测量的方差分析。与正常停止行走相比，在festination期间，步频过度增加（68%），步幅减少（69%）;当比较冻结前的步幅与正常停止时，这种模式仍然很明显。更详细地分析冻结前的三个步骤，我们发现步幅和稳定的节奏率和比例的双支持请逐步减少。步频与步长之间的关系表现出指数增加的步频与步长的减少在festination和冻结。结果表明，冻结是由一个组合的日益无力产生步幅叠加在一个失控的节奏：步行。(C)2001运动障碍协会。
We investigated the spatiotemporal variables of gait leading up to freezing. Gait analysis was carried out on 14 patients with Parkinson's disease in the off phase of the medication cycle. A computerised, three-dimensional gait analysis system was used to treasure the walking pattern. After several trials of normal walling with voluntary stopping. distracting manoeuvres and obstacles on the walkway were used to provoke freezing or festination. The gait variables of normal (off phase), festinating, prestop, and prefreezing strides were analysed using analysis of variance for repeated-measures. Cadence was excessively increased (68%) and stride length decreased (69%) during festination compared with normal off walking; a pattern which remained pronounced When comparing prefreezing strides with normal stopping. Analysing in more detail the three steps before a freeze, we found a progressive decrease of stride length and stable cadence rates and proportions of double support pleases. The relationship between cadence and stride length exhibited an exponential increase of cadence with a decreasing stride length during festination and freezing. Results suggest that freezing is caused by a combination of an increasing inability to generate stride length superimposed on a dyscontrol of the cadence: of walking. (C) 2001 Movement Disorder Society.