Changes in body mass index and alcohol and tobacco consumption among breast cancer survivors and cancer-free women: A prospective study in the Danish Diet, Cancer and Health Cohort
Changes in body mass index and alcohol and tobacco consumption among breast cancer survivors and cancer-free women: A prospective study in the Danish Diet, Cancer and Health Cohort
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DOI：
10.3109/0284186x.2012.746466
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发表时间：
2013-02-01
期刊：
影响因子：
3.1
通讯作者：
Johansen, Christoffer
中科院分区：
文献类型：
--
作者：
Bidstrup, Pernille E.;Dalton, Susanne O.;Johansen, Christoffer
背景资料。乳腺癌的诊断被认为是一个可以教育女性的时刻，因为女性更愿意改变更健康的生活方式。与其他女性相比，人们对乳腺癌患者健康行为的改变知之甚少。材料和方法。我们检查了确诊为乳腺癌的女性和未患癌症的女性的体重指数(BMI)和烟酒消费的变化。我们使用了参加饮食、癌症和健康队列的23420名年龄在50岁-之间的女性的数据，其中449人在基线(1993年-1997年)到随访(2000年-2002年)期间被诊断为乳腺癌，22971人保持无癌状态。我们使用多元线性回归分析来检验两组间体重指数、烟酒摄入量的差异，并检验人口统计学和预后因素是否与乳腺癌女性患者的行为改变有关。结果。两组在体重指数、饮酒和吸烟方面的变化没有显著差异。只有在基线和随访期间体重减轻的女性中的子分析中，乳腺癌女性比非癌症女性减轻了更多的体重(Beta=0.2；CI 0.1；0.4)，但不能排除阶段的残余混杂。在患有乳腺癌的女性中，我们发现不同教育程度、婚姻状况、化疗、激素治疗或放射治疗的女性的体重指数、烟酒消费量没有显著变化。结论。与非癌症女性相比，患有乳腺癌的女性没有降低她们的BMI，也没有改变她们的饮酒或烟草消费。这项研究表明，在癌症诊断后，需要指导方针和干预措施来改变健康行为。
Background. A breast cancer diagnosis has been suggested as a teachable moment when a woman is more open to making healthier lifestyle changes. Little is known about the health behaviour changes women with breast cancer initiate compared to those made by other women. Material and methods. We examined changes in body mass index (BMI) and tobacco and alcohol consumption among women with a diagnosis of breast cancer and among cancer-free women. We used data from 23 420 women aged 50-64 years who participated in the Diet, Cancer and Health cohort, of whom 449 were diagnosed with breast cancer between baseline (1993-1997) and follow-up (2000-2002), and 22 971 remained cancer-free. We used multiple linear regression analysis to examine differences in BMI and alcohol and tobacco consumption between the two groups and to examine whether demographic and prognostic factors were associated with behavioural changes in women with breast cancer. Results. There were no significant differences in changes in BMI, alcohol and tobacco consumption between the two groups. Only in sub-analyses among women who lost weight between baseline and follow-up, women with breast cancer lost more weight than cancer-free women (beta = 0.2; CI 0.1; 0.4), but residual confounding from stage cannot be excluded. Among the women with breast cancer we found no significant changes in BMI, alcohol and tobacco consumption by level of education, marital status, chemotherapy, hormone therapy or radiation. Conclusion. Women with breast cancer did not reduce their BMI, or modify their alcohol use or tobacco consumption compared with cancer-free women. This study indicates that guidelines and interventions to change health behaviour are needed after a cancer diagnosis.