Changes in quality of life following cognitive-behavioral therapy for obsessive-compulsive disorder
Changes in quality of life following cognitive-behavioral therapy for obsessive-compulsive disorder
复制标题
DOI：
10.1016/j.brat.2007.04.014
复制
发表时间：
2007-12-01
影响因子：
4.1
通讯作者：
Tolin, David F.
中科院分区：
文献类型：
--
作者：
Diefenbach, Gretchen J.;Abramowitz, Jonathan S.;Tolin, David F.
认知行为疗法（CBT）结合暴露和反应预防是强迫症（OCD）的一线治疗。虽然CBT在减轻强迫症症状方面的疗效已经得到了很好的证明，但其对生活质量（QOL）的影响却知之甚少。在目前的研究中，功能障碍方面的生活质量（由希恩残疾量表测量）进行了评估，在70名成人门诊强迫症患者CBT前后。在工作、社会和家庭功能方面，观察到生活质量的统计学显著改善和治疗前至治疗后的大效应量。即使在控制了抑郁症状的改善后，强迫症症状严重程度的改善也能预测社会和家庭功能的改善。此外，强迫症症状和生活质量的临床显著变化是高度相关的，虽然有一个子集的参与者，其症状改善没有相应的生活质量改善。这些结果表明，CBT的影响可能超出了强迫症症状的减少，生活质量。(C)2007爱思唯尔有限公司保留所有权利。
Cognitive-behavioral therapy (CBT) incorporating exposure and response prevention is a first line treatment for obsessive-compulsive disorder (OCD). Although, the efficacy of CBT in reducing OCD symptoms is well documented, less is known about its effects on quality of life (QOL). In the current study, functional impairment aspects of QOL (as measured by the Sheehan Disability Scale) were assessed among 70 adult outpatients with OCD before and after CBT. Statistically significant improvements in QOL and large pre- to post-treatment effect sizes were observed for work, social, and family functioning. Improvements in social and family functioning were predicted by improvements in OCD symptom severity even after controlling for improvements in depressive symptoms. In addition, clinically significant change in OCD symptoms and QOL were highly related, although there was a subset of participants whose symptoms improved without corresponding improvements in QOL. These results suggest that the effects of CBT may extend beyond OCD symptom reduction to QOL. (C) 2007 Elsevier Ltd. All rights reserved.