Greater loss of productivity among Japanese workers with gastroesophageal reflux disease (GERD) symptoms that persist vs resolve on medical therapy.
Greater loss of productivity among Japanese workers with gastroesophageal reflux disease (GERD) symptoms that persist vs resolve on medical therapy.
复制标题
患有胃食管反流病 (GERD) 症状的日本工人的生产力损失更大，这种症状持续存在，而不是通过药物治疗得到缓解。
DOI：
10.1111/nmo.12319
复制
发表时间：
2014
期刊：
影响因子：
--
通讯作者：
J.M.
中科院分区：
文献类型：
--
作者：
Suzuki;H.;Matsuzaki;J.;Masaoka;T.;Inadomi;J.M.
背景胃-食道反流病(GERD)损害生活质量；然而，GERD与工作效率之间的关系在日本尚未得到很好的研究。这项研究旨在比较GERD症状持续存在和内科治疗后缓解的日本工人GERD对生产力的影响。方法采用横断面网络调查。使用用于GERD患者的网络报告的工作生产力和活动受损问卷和GERD症状严重程度问卷来评估GERD对工作和日常生产力的影响。研究对象还包括人口统计学资料、临床病史和对GERD药物的满意度。在排除了有胃肠道恶性肿瘤、消化性溃疡、上消化道手术和失业病史的患者后，650名参与者被纳入分析。持续有GERD症状的参与者报告的工作效率(11.4±13.4)小时/周、旷工(0.7±33.1)小时/周、出勤(10.7±12.6)小时/周、费用(20/100±26/800日元/周)和较低的日生产率(71.3%[95%可信区间，69.0-73.7])显著高于那些症状得到缓解的患者。在有持续性胃肠道反流病症状的参与者中，对胃肠道反流病药物的不满意程度与失去工作和日常生产力显著相关(p<；0.001)。结论与推断尽管进行了药物治疗，胃肠道反流病对工作和日常生产力造成了巨大的负担。无效的GERD治疗与更大的生产力损失有关。
BackgroundGastro‐esophageal reflux disease (GERD) impairs quality of life; however, the association between GERD and work productivity has not been well investigated in Japan. This study was designed to compare the impact of GERD on productivity between Japanese workers with GERD symptoms that persistedvsresolved on medical therapy.MethodsA cross‐sectional Web‐based survey was conducted in workers. The impact of GERD on work and daily productivity was evaluated using a Web‐reported Work Productivity and Activity Impairment Questionnaire for patients with GERD and a GERD symptom severity Questionnaire. Demographic information, clinical history, and satisfaction with GERD medication were also ascertained.Key ResultsA total of 20 000 subjects were invited to the survey. After the exclusion of patients with a history of gastrointestinal (GI) malignancy, peptic ulcer, upper GI surgery, and unemployment, 650 participants were included in the analysis. Participants with persistent GERD symptoms reported a significantly greater losses of work productivity (11.4 ± 13.4 h/week), absenteeism (0.7 ± 3.1 h/week), presenteeism (10.7 ± 12.6 h/week), costs (20 100 ± 26 800 JPY/week), and lower daily productivity (71.3% [95% confidence interval, 69.0–73.7]) than those whose symptoms were alleviated with medications. The level of dissatisfaction with GERD medications among participants with persistent GERD symptoms was significantly correlated with loss of work and daily productivity (p< 0.001).Conclusions & InferencesGERD places a significant burden on work and daily productivity despite medical therapy. Ineffective GERD therapy is associated with greater productivity loss.