Iodine deficiency disorders in Bangladesh
Iodine deficiency disorders in Bangladesh
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孟加拉国的碘缺乏病
DOI：
10.1007/bf02823878
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发表时间：
1996
影响因子：
4.3
通讯作者：
C. Pandav
中科院分区：
文献类型：
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作者：
H. Yusuf;S. Quazi;M. R. Kahn;M. Mohiduzzaman;Bardrun Nahar;M. M. Rahman;M. N. Islam;M. A. Khan;M. Shahidullah;T. Hoque;M. Baquer;C. Pandav
1993年在孟加拉国进行了一次广泛的碘缺乏病调查，以评估该国最新的碘营养状况。调查的临床变量为甲状腺肿和克汀病，生化变量为尿碘。在选择调查地点时，采用了“EPI-30聚类”抽样方法。在每个调查点，研究人口包括5-11岁的男孩和女孩，以及15-44岁的男子和妇女，人口数量大致相等。调查共涉及七十八个地点，受访者总数为三万零七十二人。尿液样本总数为4512（15%子样本）。孟加拉国目前的甲状腺肿总发病率（1级+2级）为47.1%（丘陵地区44.4%;易发洪水地区50.7%;平原地区45.6%）。克汀病在全国的流行率为0.5%（丘陵地区0.8%;易发洪水地区0.5%;平原地区0.3%）。近69%的孟加拉国人口患有生化碘缺乏症（尿碘排泄量<10毫克/分升）（丘陵地区84.4%;易发洪水地区67.1%;平原地区60.4%）。从甲状腺肿发病率和UIE来看，妇女和儿童比男子受影响更大。所有生态区普遍严重缺碘，表明全国是缺碘地区。根据调查的经验提出了具有全球意义的重要建议。
An extensive iodine deficiency disorders survery was conducted in Bangladesh in 1993 to assess the latest iodine nutriture status of the country. The clinical variables of the survey were goitre and cretinism, and the biochemical variable was urinary iodine. The “EPI-30 cluster” sampling methodology was followed for selecting the survey sites. In each survey site, the study population consisted of boys and girls, aged 5–11 years, and men and women, aged 15–44 years, in about equal populations. the total number of survey sites was 78 and the total number of respondents was 30 072. The total number of urine samples was 4512 (15% sub-sample). The current total goitre rate (grade 1+grade 2) in Bangladesh is 47.1% (hilly, 44.4%; flood-prone, 50.7%; and plains, 45.6%). The prevalence of cretinism in the country is 0.5% (hilly, 0.8%; flood-prone, 0.5%; and plains, 0.3%). Nearly 69% of Bangladeshi population have biochemical iodine deficiency (urinary iodine excretion [UIE]<10 mg/dl) (hilly, 84.4; flood-prone, 67.1%; and plains 60.4%). Women and children are more affected than men, in terms of both goitre prevalence and UIE. The widespread severe iodine deficiency in all ecological zones indicates that the country as a whole is an iodine-deficient region. Important recommendations of global interest are made from the experience of the survey.