Uptake of Lp (a) lipoprotein by cultured fibroblasts.
Uptake of Lp (a) lipoprotein by cultured fibroblasts.
复制标题
培养的成纤维细胞对 Lp (a) 脂蛋白的摄取。
DOI：
10.1016/s0006-291x(81)80179-9
复制
发表时间：
1981
影响因子：
3.1
通讯作者：
Bierman,EL
中科院分区：
文献类型：
--
作者：
Floren,CH;Albers,JJ;Bierman,EL
Lp（a）脂蛋白被培养的人成纤维细胞结合和吸收，并增加细胞胆固醇含量和胆固醇酯化。在低密度脂蛋白受体阴性细胞中，细胞胆固醇含量和胆固醇酯化的增加是最小的，这表明Lp（a）脂蛋白通过低密度脂蛋白受体途径摄取。
Lp(a) lipoprotein is bound and taken up by cultured human fibroblasts and increases cell cholesterol content and cholesterol esterification. The increase in cell cholesterol content and cholesterol esterification in low density lipoprotein receptor negative cells was minimal, which suggests that Lp(a) lipoprotein was taken up by the low density lipoprotein receptor pathway.