SPCalc: A web-based calculator for sample size and power calculations in micro-array studies.
SPCalc: A web-based calculator for sample size and power calculations in micro-array studies.
复制标题
DOI：
10.6026/97320630001251
复制
发表时间：
2006-11-22
期刊：
影响因子：
1.9
通讯作者：
Lee, Mei-Ling Ting
中科院分区：
文献类型：
--
作者：
Qiu, Weiliang;Lee, Mei-Ling Ting
Calculation of the appropriate sample size in planning microarray studies is important because sample collection can be expensive and time-consuming. Sample-size calculation is also a challenging issue for microarray studies because the number of genes is far larger than the number of samples so that traditional methods of sample-size calculation cannot be directly applied. To help investigators answer the question of how many samples are needed in their microarray studies, we developed a user-friendly web-based calculator, SPCalc, for calculating sample size and power for a variety of commonly used experimental designs, including completely randomized treatmentcontrol design, matched-pairs design, multiple-treatment design having an isolated treatment effect, and randomized block design. The web-based calculator SPCalc is publicly available at http://www.biostat.harvard.edu /people/faculty/mltlee/webfront-r.html
