25-YEAR PROSPECTIVE MORTALITY STUDY IN SPINAL-CORD INJURED PATIENT - COMPARISON WITH LONG-TERM LIVING PARAPLEGIC

25-YEAR PROSPECTIVE MORTALITY STUDY IN SPINAL-CORD INJURED PATIENT - COMPARISON WITH LONG-TERM LIVING PARAPLEGIC
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DOI:
10.1016/s0022-5347(17)58506-7
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发表时间:
1977-01-01
期刊:
影响因子:
6.6
通讯作者:
HACKLER, RH
HACKLER, RH
中科院分区:
医学1区
文献类型:
--
作者:
HACKLER, RH

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两项研究相结合,对 270 名脊髓损伤患者进行了 25 年的前瞻性随访,对 175 名截瘫患者进行了 20 多年(平均 24.2 年)的评估。 25年后死亡率为49%,其中肾脏疾病是主要死因(43%)。在脊髓生命的最后五年中,血管性死亡同样普遍。一些患者能够长期生存(超过 20 年)可能有几个原因,包括患者积极性(更好的随访)、较少的血管问题、较少的慢性褥疮以及较高比例的下运动神经元病变。下运动神经元病变的患者膀胱状态最佳,上尿路恶化较少。
Two studies, a 25 yr prospective followup on 270 spinal cord injury patients and a more than 20 yr (average 24.2 yr) evaluation of 175 paraplegics, are combined. The mortality rate was 49% after 25 yr, with renal disease as the major cause of death (43%). Vascular deaths were just as prevalent during the last 5 yr of spinal cord life. There are probably several reasons why some patient have long-term survival (more than 20 yr), including patient motivation (better followup), less vascular problems, less chronic decubitus and and a higher percentage of lower motor neuron lesions. Patients with lower motor neuron lesions had the best bladder status associated with less upper tract deterioration.