Analysis of visual field progression in glaucoma
Analysis of visual field progression in glaucoma
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DOI：
10.1136/bjo.80.1.40
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发表时间：
1996-01-01
影响因子：
4.1
通讯作者：
Crabb, DP
中科院分区：
文献类型：
--
作者：
Fitzke, FW;Hitchings, RA;Crabb, DP
背景--尽管计算机化视野检查得到了广泛的应用，但随着时间的推移，后续青光眼患者的视野恶化的诊断仍然特别困难。提出了一种新的利用纵场数据的图形显示进行分析的新方法。方法-将来自一系列场的定量数据转换为颜色编码形式，以说明变化的空间构型，以辅助场损失的解释。介绍了分析方法和研制的计算机软件(Progressor)。与STAT-PAC-2青光眼变化概率分析进行了比较，包括使用正常眼压性青光眼患者的10只眼的一系列视野进行青光眼变化概率分析的一致性程度。区分进展和稳定视网膜位置的技术之间的一致性水平很好(kappa=0.62；SE=0.04)。结论-这种新技术将视野敏感度随时间的变化与显著变化的颜色编码结合到一幅图像中，可能提供一种有效的方法来检测青光眼视野丧失的真实进展。
Background - Despite the widespread use of computerised perimetry the diagnosis of visual field deterioration in following glaucoma patients over time remains particularly difficult. A new method of analysis using a novel graphical display of longitudinal field data is presented.Methods - A linear regression model of the luminance sensitivity at each stimulus location against time of follow up transforms the quantitative data from a series of fields into a colour coded form which illustrates the spatial configuration of change to aid the interpretation of field loss. The method of analysis and the developed computer software (PROGRESSOR) is described. Comparison with STAT-PAC-2 glaucoma change probability analysis is given including levels of agreement between the techniques using series of fields of 10 eyes from patients with normal tension glaucoma.Results - Examples of this new method compare well with STATPAC-2 analysis. The level of agreement between the techniques to separate progressing from stable retinal locations is good (kappa = 0.62; SE = 0.04).Conclusions - This new technique, which combines the change in perimetric sensitivity over time with colour coding of significant change into one image may provide an efficient method to detect true progression in glaucomatous field loss.