Common and Unique Risk Factors and Comorbidity for 12-Month Mood and Anxiety Disorders Among Canadians

Common and Unique Risk Factors and Comorbidity for 12-Month Mood and Anxiety Disorders Among Canadians
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DOI:
10.1177/070674371205700806
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发表时间:
2012-08-01
影响因子:
4
通讯作者:
D'Arcy, Carl
D'Arcy, Carl
中科院分区:
医学3区
文献类型:
--
作者:
Meng, Xiangfei;D'Arcy, Carl

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目的:探讨心境障碍和焦虑障碍的共同和独特危险因素。什么样的社会人口统计学、心理学和生理学危险因素与心境和焦虑障碍及其合并症相关?多重风险因素的影响是什么?方法:从加拿大社区健康调查的数据:心理健康和幸福进行了分析。采用适当的抽样权重和自举方差估计。多元Logistic回归分析估计比值比和置信区间。结果:任何心境障碍的年患病率为5.2%,任何焦虑障碍为4.7%。抑郁症是最常见的情绪和焦虑障碍(4.8%),其次是社交恐怖症,惊恐障碍,躁狂症和广场恐怖症。在情绪和焦虑障碍患者中,22.4%的人患有2种或2种以上的疾病。情绪和焦虑症的常见风险因素是年轻,家庭收入较低,未婚,经历更大的压力,心理健康状况较差,以及有医疗条件。发现了独特的风险因素:重度抑郁发作和社交恐惧症与出生在加拿大有关;惊恐障碍与高加索人有关;教育程度低与惊恐和广场恐怖症有关;身体健康状况差与躁狂和广场恐怖症有关。那些年轻、未婚、没有充分就业、有医疗条件、压力较大、自我评估心理健康状况较差、对生活不满意的人,更有可能患有共病情绪和(或)焦虑症。随着常见危险因素数量的增加,有情绪和焦虑症的概率也increasing.Conclusions:情绪和焦虑症存在共同和独特的危险因素。风险因素是增加疾病可能性的叠加因素。
Objective: To explore the common and unique risk factors for mood and anxiety disorders. What sociodemographic, psychological, and physical risk factors are associated with mood and anxiety disorders and their comorbidities? What is the impact of multiple risk factors?Method: Data from the Canadian Community Health Survey: Mental Health and Well-Being were analyzed. Appropriate sampling weights and bootstrap variance estimation were employed. Multiple logistic regression was used to estimate odds ratios and confidence intervals.Results: The annual prevalence of any mood disorder was 5.2%, and of any anxiety disorder 4.7%. Major depressive episode was the most prevalent mood and anxiety disorder (4.8%), followed by social phobia, panic disorder, mania, and agoraphobia. Among people with mood and anxiety disorders, 22.4% had 2 or more disorders. Risk factors common to mood and anxiety disorders were being young, having lower household income, being unmarried, experiencing greater stress, having poorer mental health, and having a medical condition. Unique risk factors were found: major depressive episode and social phobia were associated with being born in Canada; panic disorder was associated with being Caucasian; lower education was associated with panic and agoraphobia; and poor physical health was associated with mania and agoraphobia. People who were young, unmarried, not fully employed, and had a medical condition, greater stress, poorer self-rated mental health, and dissatisfaction with life, were more likely to have a comorbid mood and (or) anxiety disorder. As the number of common risk factors increases, the probability of having mood and anxiety disorders also increases.Conclusions: Common and unique risk factors exist for mood and anxiety disorders. Risk factors are additive in increasing the likelihood of disease.