Investigations into self-association of vancomycin covalent dimers using surface plasmon resonance technology
Investigations into self-association of vancomycin covalent dimers using surface plasmon resonance technology
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DOI：
10.1016/s0960-894x(99)00402-3
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发表时间：
1999-08-16
影响因子：
2.7
通讯作者：
Yu, ZG
中科院分区：
文献类型：
--
作者：
Adamczyk, M;Moore, JA;Yu, ZG
通过糖肽抗生素的万古胺糖部分连接的万古霉素的共价二聚体已经以67-69%的产率一步合成。使用表面等离子体共振技术评价这些和相关万古霉素共价二聚体的自缔合倾向。(C)1999 Elsevier Science Ltd.保留所有权利。
Covalent dimers of vancomycin linked through the vancosamine sugar moieties of the glycopeptide antibiotic have been synthesized in one step in 67-69% yield. The propensity for self-association of these and related vancomycin covalent dimers is evaluated using surface plasmon resonance technology. (C) 1999 Elsevier Science Ltd. All rights reserved.