ERYTHROCYTE RECEPTORS FOR (PLASMODIUM-KNOWLESI) MALARIA - DUFFY BLOOD-GROUP DETERMINANTS
ERYTHROCYTE RECEPTORS FOR (PLASMODIUM-KNOWLESI) MALARIA - DUFFY BLOOD-GROUP DETERMINANTS
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DOI：
10.1126/science.1145213
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发表时间：
1975-01-01
期刊：
影响因子：
56.9
通讯作者：
ROTHMAN, IK
中科院分区：
文献类型：
--
作者：
MILLER, LH;MASON, SJ;ROTHMAN, IK
Duffy血型阴性的人红细胞（FyFy）对诺氏疟原虫（一种感染Duffy阳性人红细胞的猴疟疾）的感染具有抗性。P。知识抵抗因子，达菲阴性红细胞，在西非发生的频率很高，那里的人对间日疟有抵抗力。这表明Duffy血型决定簇（FyaorFyb）可能是P的红细胞受体。间日疟原虫
Duffy blood group negative human erythrocytes (FyFy) are resistant to infection byPlasmodium knowlesi, a simian malaria that infects Duffy positive human erythrocytes. TheP. knowlesiresistance factor, Duffy negative erythrocytes, occurs in high frequency in West Africa, where the people are resistant to vivax malaria. This suggests that Duffy blood group determinants (FyaorFyb) may be erythrocyte receptors forP. vivax.