Detection of heavy metal ions in drinking water using a high-resolution differential surface plasmon resonance sensor
Detection of heavy metal ions in drinking water using a high-resolution differential surface plasmon resonance sensor
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DOI：
10.1021/es049234z
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发表时间：
2005-03-01
影响因子：
11.4
通讯作者：
Tao, NJ
中科院分区：
文献类型：
--
作者：
Forzani, ES;Zhang, HQ;Tao, NJ
我们已经建立了一个高分辨率的差分表面等离子体共振（SPR）传感器检测重金属离子。传感器表面分为参考区和感测区，并且来自这两个区域的SPR角度的差被四分之一单元光电探测器检测为差分信号。在存在金属离子的情况下，由于金属离子特异性结合到涂覆有适当选择的肽的感测区域上，差分信号发生变化，这提供了金属离子的准确实时测量和定量。通过用肽NH 2 Gly-Gly-His-COOH和NH 2-（HiS）（6）-COOH涂覆传感表面，实现了在ppt-ppb范围内对Cu 2+和Ni 2+的选择性检测。利用该传感器对饮用水中的Cu ~（2+）进行了检测。
We have built a high-resolution differential surface plasmon resonance (SPR) sensor for heavy metal ion detection. The sensor surface is divided into a reference and sensing areas, and the difference in the SPR angles from the two areas is detected with a quadrant cell photodetector as a differential signal. In the presence of metal ions, the differential signal changes due to specific binding of the metal ions onto the sensing area coated with properly selected peptides, which provides an accurate real-time measurement and quantification of the metal ions. Selective detection of CU2+ and Ni2+ in the ppt-ppb range was achieved by coating the sensing surface with peptides NH2Gly-Gly-His-COOH and NH2-(HiS)(6)-COOH. CU2+ in drinking water was tested using this sensor.